Clinical trials
Amyotrophic Lateral Sclerosis trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
434 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 1 |
| 2001 | 4 |
| 2002 | 4 |
| 2003 | 5 |
| 2004 | 5 |
| 2005 | 9 |
| 2006 | 10 |
| 2007 | 11 |
| 2008 | 14 |
| 2009 | 14 |
| 2010 | 10 |
| 2011 | 13 |
| 2012 | 13 |
| 2013 | 23 |
| 2014 | 5 |
| 2015 | 20 |
| 2016 | 21 |
| 2017 | 24 |
| 2018 | 20 |
| 2019 | 20 |
| 2020 | 29 |
| 2021 | 32 |
| 2022 | 19 |
| 2023 | 12 |
| 2024 | 20 |
| 2025 | 27 |
| 2026 | 30 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 235 |
| Recruiting | 74 |
| Terminated | 40 |
| Active, not recruiting | 27 |
| Unknown status | 17 |
| Withdrawn | 11 |
| Not yet recruiting | 11 |
| Enrolling by invitation | 6 |
| No longer available | 5 |
| Suspended | 3 |
| Temporarily not available | 2 |
| Available | 2 |
| Approved for marketing | 1 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Massachusetts General Hospital | 19 |
| Johns Hopkins University | 12 |
| Mayo Clinic | 10 |
| National Institute of Neurological Disorders and Stroke (NINDS) | 10 |
| University of Michigan | 10 |
| Cytokinetics | 9 |
| Drexel University College of Medicine | 9 |
| Merit E. Cudkowicz, MD | 9 |
| Biogen | 8 |
| Duke University | 8 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Amyotrophic Lateral Sclerosis | 434 |
| Motor Neuron Disease | 78 |
| Neurodegenerative Diseases | 26 |
| Parkinson Disease | 25 |
| Spinal Cord Injuries | 23 |
| Multiple Sclerosis | 19 |
| Neuromuscular Diseases | 18 |
| Alzheimer Disease | 17 |
| Muscular Atrophy, Spinal | 17 |
| Nervous System Diseases | 16 |
Trials
Showing 26 to 50 of 434. Each trial links to its page on Pharma Observatory.
334 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
Go deeper on Pharma Observatory
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