Clinical trials
Phase 2 Major Depressive Disorder trials
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
398 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2001 | 4 |
| 2002 | 4 |
| 2003 | 9 |
| 2004 | 10 |
| 2005 | 10 |
| 2006 | 10 |
| 2007 | 18 |
| 2008 | 24 |
| 2009 | 16 |
| 2010 | 15 |
| 2011 | 15 |
| 2012 | 14 |
| 2013 | 13 |
| 2014 | 15 |
| 2015 | 12 |
| 2016 | 13 |
| 2017 | 12 |
| 2018 | 14 |
| 2019 | 13 |
| 2020 | 15 |
| 2021 | 23 |
| 2022 | 15 |
| 2023 | 20 |
| 2024 | 31 |
| 2025 | 24 |
| 2026 | 23 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 259 |
| Recruiting | 46 |
| Terminated | 38 |
| Unknown status | 21 |
| Withdrawn | 13 |
| Active, not recruiting | 10 |
| Not yet recruiting | 8 |
| Suspended | 2 |
| Enrolling by invitation | 1 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| National Institute of Mental Health (NIMH) | 15 |
| GlaxoSmithKline | 14 |
| Janssen Research & Development, LLC | 14 |
| Massachusetts General Hospital | 14 |
| Alto Neuroscience | 7 |
| H. Lundbeck A/S | 7 |
| Icahn School of Medicine at Mount Sinai | 7 |
| AstraZeneca | 6 |
| Otsuka Pharmaceutical Development & Commercialization, Inc. | 6 |
| Shanghai Mental Health Center | 6 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Major Depressive Disorder | 398 |
| Depressive Disorder | 40 |
| Depressive Disorder, Treatment-Resistant | 40 |
| Mood Disorders | 30 |
| Anxiety Disorders | 16 |
| Mental Disorders | 15 |
| Bipolar Disorder | 13 |
| Inflammation | 10 |
| Alcoholism | 9 |
| Anhedonia | 7 |
Trials
Showing 26 to 50 of 398. Each trial links to its page on Pharma Observatory.
298 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
No changes to these trials in the last 7 days.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.