Clinical trials
Phase 3 Major Depressive Disorder trials
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
388 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2001 | 6 |
| 2002 | 16 |
| 2003 | 9 |
| 2004 | 16 |
| 2005 | 21 |
| 2006 | 27 |
| 2007 | 13 |
| 2008 | 15 |
| 2009 | 18 |
| 2010 | 24 |
| 2011 | 29 |
| 2012 | 18 |
| 2013 | 13 |
| 2014 | 14 |
| 2015 | 12 |
| 2016 | 10 |
| 2017 | 6 |
| 2018 | 16 |
| 2019 | 10 |
| 2020 | 12 |
| 2021 | 10 |
| 2022 | 9 |
| 2023 | 8 |
| 2024 | 12 |
| 2025 | 19 |
| 2026 | 16 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 289 |
| Recruiting | 31 |
| Terminated | 30 |
| Withdrawn | 13 |
| Not yet recruiting | 8 |
| Unknown status | 7 |
| Active, not recruiting | 7 |
| Suspended | 2 |
| Enrolling by invitation | 1 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Eli Lilly and Company | 21 |
| H. Lundbeck A/S | 21 |
| Forest Laboratories | 18 |
| Otsuka Pharmaceutical Development & Commercialization, Inc. | 18 |
| Wyeth is now a wholly owned subsidiary of Pfizer | 18 |
| AstraZeneca | 14 |
| Janssen Research & Development, LLC | 13 |
| Takeda | 13 |
| Sanofi | 11 |
| Naurex, Inc, an affiliate of Allergan plc | 10 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Major Depressive Disorder | 388 |
| Depressive Disorder | 35 |
| Mood Disorders | 13 |
| Depressive Disorder, Treatment-Resistant | 12 |
| Mental Disorders | 12 |
| Bipolar Disorder | 11 |
| Psychotic Disorders | 11 |
| Sleep Initiation and Maintenance Disorders | 8 |
| Anxiety Disorders | 6 |
| Schizophrenia | 5 |
Trials
Showing 26 to 50 of 388. Each trial links to its page on Pharma Observatory.
288 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
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