Clinical trials
Completed Major Depressive Disorder trials
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
1,789 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 7 |
| 2001 | 19 |
| 2002 | 37 |
| 2003 | 33 |
| 2004 | 53 |
| 2005 | 64 |
| 2006 | 81 |
| 2007 | 81 |
| 2008 | 86 |
| 2009 | 84 |
| 2010 | 91 |
| 2011 | 117 |
| 2012 | 93 |
| 2013 | 71 |
| 2014 | 81 |
| 2015 | 86 |
| 2016 | 89 |
| 2017 | 75 |
| 2018 | 67 |
| 2019 | 72 |
| 2020 | 67 |
| 2021 | 94 |
| 2022 | 80 |
| 2023 | 55 |
| 2024 | 47 |
| 2025 | 19 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 1,789 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Massachusetts General Hospital | 58 |
| Eli Lilly and Company | 54 |
| National Institute of Mental Health (NIMH) | 47 |
| New York State Psychiatric Institute | 39 |
| Centre for Addiction and Mental Health | 32 |
| H. Lundbeck A/S | 31 |
| AstraZeneca | 30 |
| Otsuka Pharmaceutical Development & Commercialization, Inc. | 28 |
| University of California, Los Angeles | 28 |
| Forest Laboratories | 27 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Major Depressive Disorder | 1,789 |
| Bipolar Disorder | 145 |
| Depressive Disorder | 141 |
| Anxiety Disorders | 86 |
| Mood Disorders | 81 |
| Schizophrenia | 72 |
| Depressive Disorder, Treatment-Resistant | 68 |
| Psychotic Disorders | 54 |
| Mental Disorders | 47 |
| Stress Disorders, Post-Traumatic | 46 |
Trials
Showing 26 to 50 of 1,789. Each trial links to its page on Pharma Observatory.
1,689 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
No changes to these trials in the last 7 days.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.