Clinical trials
Down Syndrome trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
200 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2001 | 2 |
| 2002 | 1 |
| 2004 | 1 |
| 2005 | 2 |
| 2006 | 3 |
| 2007 | 2 |
| 2008 | 7 |
| 2009 | 10 |
| 2010 | 8 |
| 2011 | 5 |
| 2012 | 8 |
| 2013 | 10 |
| 2014 | 10 |
| 2015 | 13 |
| 2016 | 6 |
| 2017 | 5 |
| 2018 | 13 |
| 2019 | 8 |
| 2020 | 11 |
| 2021 | 16 |
| 2022 | 9 |
| 2023 | 13 |
| 2024 | 7 |
| 2025 | 10 |
| 2026 | 18 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 114 |
| Recruiting | 39 |
| Terminated | 21 |
| Unknown status | 10 |
| Active, not recruiting | 7 |
| Not yet recruiting | 4 |
| Enrolling by invitation | 3 |
| Withdrawn | 2 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| University of Colorado, Denver | 12 |
| Natera, Inc. | 8 |
| Sequenom, Inc. | 8 |
| University of Kansas Medical Center | 8 |
| Children's Hospital Medical Center, Cincinnati | 7 |
| Hoffmann-La Roche | 6 |
| Oregon Health and Science University | 5 |
| University of Michigan | 5 |
| Children's Hospital of Philadelphia | 4 |
| Duke University | 4 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Down Syndrome | 200 |
| Alzheimer Disease | 21 |
| Trisomy 18 Syndrome | 21 |
| Trisomy 13 Syndrome | 19 |
| Sleep Apnea, Obstructive | 16 |
| Turner Syndrome | 13 |
| Aneuploidy | 12 |
| Intellectual Disability | 11 |
| Cerebral Palsy | 8 |
| Sex Chromosome Aberrations | 7 |
Trials
Showing 26 to 50 of 200. Each trial links to its page on Pharma Observatory.
100 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
Go deeper on Pharma Observatory
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