Completed Hyponatremia trials: Trial Insights

Filters: Condition: Hyponatremia Status: Completed Clear all

96 trials match Source: ClinicalTrials.gov registrations

Trials started per year
Category	Trials
2000	2
2001	2
2002	1
2003	2
2004	4
2005	2
2006	2
2007	6
2008	7
2009	5
2010	5
2011	5
2012	4
2013	8
2014	7
2015	3
2016	7
2017	4
2018	4
2019	2
2020	3
2021	4
2022	3
2023	1
2024	3

Trials by status
Category	Trials
Completed	96

Top lead sponsors
Category	Trials
University Hospital, Basel, Switzerland	9
Cumberland Pharmaceuticals	7
Sanofi	5
Otsuka Pharmaceutical Development & Commercialization, Inc.	4
University of Cologne	4
Otsuka Pharmaceutical Europe Ltd	3
CardioKine Inc.	2
Hospital General de Niños Pedro de Elizalde	2
Hospital Italiano de Buenos Aires	2
University Hospital, Caen	2

Top conditions
Category	Trials
Hyponatremia	96
Inappropriate ADH Syndrome	18
Diabetes Insipidus	9
Edema	8
Hypernatremia	6
Fibrosis	5
Heart Failure	5
Hepatic Encephalopathy	3
Hypovolemia	3
Renal Insufficiency	3

Trials

Showing 51 to 75 of 96. Each trial links to its page on Pharma Observatory.

Characterisation of Neuropsychological and Motoric Performance in Patients With Hyponatremia NCT01879774Not applicableCompletedUniversity of CologneStarted 2012
Sodium Management in Acute Neurological Injury NCT01558843ObservationalCompletedWashington University School of MedicineStarted 2012
Effect of Hyponatremia in Small Cell Lung Cancer NCT04451460ObservationalCompletedAnkara City Hospital BilkentStarted 2012
Copeptin in the Differential Diagnosis of Dysnatremia in Hospitalized Patients NCT01456533ObservationalCompletedUniversity Hospital, Basel, SwitzerlandStarted 2011
V2 Receptor Effects on Fluid Regulation and Performance NCT02084797Not applicableCompletedOakland UniversityStarted 2011
Tolvaptan in Hyponatremic Cancer Patients NCT01199198Phase 4CompletedM.D. Anderson Cancer CenterStarted 2011
Effect of Tolvaptan on Cognitive Function in Cirrhosis NCT01556646Phase 3CompletedHunter Holmes Mcguire Veteran Affairs Medical CenterStarted 2011
0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Critically Ill Children NCT01301274Not applicableCompletedHospital General de Niños Pedro de ElizaldeStarted 2011
Hyponatremia in the Elderly: Benefit From a Change in Drug Therapy? NCT01212211Not applicableCompletedUniversity Hospital, CaenStarted 2010
Variation in Natremia Using Two Different Maintenance Intravenous Fluids in Postsurgical Hospitalized Children NCT01251770Phase 3CompletedHospital General de Niños Pedro de ElizaldeStarted 2010
Hyponatremia Registry for Patients With Euvolemic and Hypervolemic Hyponatremia NCT01240668ObservationalCompletedOtsuka America PharmaceuticalStarted 2010
Incidence of Hyponatremia in PEG-SD Compared to PEG-ELS NCT01299779Not applicableCompletedThomas Jefferson UniversityStarted 2010
Post Operative Hyponatremia in the Renal Transplant Population NCT01456832ObservationalCompletedMayo ClinicStarted 2010
Efficacy Study of VA106483 in Males With Nocturia. NCT01038843Phase 2CompletedVantia LtdStarted 2009
Do Changes in Plasma Osmolality Influence Ventilation? NCT01008644Phase 1CompletedVibeke MoenStarted 2009
Study to Compare Conivaptan Pharmacokinetics in Subjects With Mild & Moderate Kidney Function Impairment to Subjects With Normal Kidney Function NCT00887627Phase 1CompletedCumberland PharmaceuticalsStarted 2009
Study to Compare Conivaptan in Subjects With Mild & Moderate Liver Impairment Versus Subjects With Normal Liver Function NCT00851227Phase 1CompletedCumberland PharmaceuticalsStarted 2009
Tolvaptan Versus Fluid Restriction in SIADH NCT04119206ObservationalCompletedUniversity of Erlangen-Nürnberg Medical SchoolStarted 2009
Effect of Midodrine and Albumine in the Prevention of Complications in Cirrhotic Patients Awaiting Liver Transplantation NCT00839358Phase 4CompletedHospital Clinic of BarcelonaStarted 2008
Pico-Salax Colonic Preparation Study: Quantifying Electrolyte and Volume Status Changes NCT00885430Phase 4CompletedQueen's UniversityStarted 2008
A Phase 2 Efficacy and Safety Study of the Tolvaptan Tablets in Patients With Non-hypovolemic Non-acute Hyponatremia NCT00664014Phase 2CompletedOtsuka Beijing Research InstituteStarted 2008
Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Oral Lixivaptan Capsules in Subject With Euvolemic Hyponatremia NCT00660959Phase 3CompletedCardioKine Inc.Started 2008
Hypotonic Versus Isotonic Parenteral (HIP) Fluid Trial NCT00734214Phase 3CompletedHamilton Health Sciences CorporationStarted 2008
Subclassification of the Syndrome of Inappropriate ADH Secretion NCT01341665ObservationalCompletedUniversity of WuerzburgStarted 2008
Hypertonic Saline Solution in Heart Failure NCT00555685Phase 2CompletedUniversity of Sao PauloStarted 2008

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