Observational Multiple Organ Failure trials: Trial Insights

Filters: Condition: Multiple Organ Failure Phase: Observational Clear all

95 trials match Source: ClinicalTrials.gov registrations

Trials started per year
Category	Trials
2003	1
2004	1
2005	1
2007	2
2008	4
2009	2
2011	2
2012	2
2013	4
2014	3
2015	4
2016	4
2017	5
2018	7
2019	7
2020	7
2021	2
2022	7
2023	5
2024	6
2025	6
2026	12

Trials by status
Category	Trials
Completed	39
Unknown status	30
Not yet recruiting	11
Recruiting	8
Active, not recruiting	4
Terminated	1
Enrolling by invitation	1
Withdrawn	1

Top lead sponsors
Category	Trials
University of Ulm	4
Chang Gung Memorial Hospital	3
Assiut University	2
Croatian Society for Organ Support	2
Hai Li	2
Henry M. Jackson Foundation for the Advancement of Military Medicine	2
IRCCS Azienda Ospedaliero-Universitaria di Bologna	2
Karolinska Institutet	2
Massachusetts General Hospital	2
Osijek University Hospital	2

Top conditions
Category	Trials
Multiple Organ Failure	95
Sepsis	30
Critical Illness	23
Shock, Septic	19
Acute Kidney Injury	12
Respiratory Distress Syndrome	10
Systemic Inflammatory Response Syndrome	10
Infections	8
Inflammation	8
Shock	8

Trials

Showing 76 to 95 of 95. Each trial links to its page on Pharma Observatory.

LDH as a Biochemical Biomarker to Predict Organ Failure in the Emergency Department Setting NCT01937676ObservationalCompletedKarolinska InstitutetStarted 2013
Application of Biomarkers Change to Predict Outcome of Patient With Severe Sepsis NCT02871895ObservationalUnknown statusChang Gung Memorial HospitalStarted 2013
Application of Stimulated Immune Response Change to Predict Outcome of Patient With Severe Sepsis NCT02887274ObservationalUnknown statusChang Gung Memorial HospitalStarted 2013
Effects of Continuous Veno-venous Haemofiltration on Plasma Lactate in Critically Ill Patients NCT01824771ObservationalCompletedFirst Affiliated Hospital, Sun Yat-Sen UniversityStarted 2013
Prediction Study of Complications After Severe Trauma NCT01713205ObservationalUnknown statusJiang JianxinStarted 2012
TCF7L2 Polymorphisms Influence on Glycemic Control in ICU Patients With Organ Failure NCT03055169ObservationalCompletedUniversity Hospital, LilleStarted 2012
Biomarker of Lung Injury in ARDS Patients Receiving ECMO Support NCT01967602ObservationalUnknown statusNational Taiwan University HospitalStarted 2011
Severe Sepsis/Septic Shock on Admission to the General Surgical ICU NCT01363635ObservationalUnknown statusMahidol UniversityStarted 2011
Citrate Pharmacokinetics and Regional Citrate Anticoagulation in CRRT NCT00948558ObservationalUnknown statusHuashan HospitalStarted 2009
The Prognostic Assessment of Extubation in Aged Patients With Multiple Organ Dysfunction Syndrome NCT01802983ObservationalUnknown statusChinese PLA General HospitalStarted 2009
NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock NCT00736723ObservationalCompletedUniversity of UlmStarted 2008
BK Virus and Renal Dysfunction in Postoperative/Posttraumatic Critically Ill Patients NCT00736827ObservationalCompletedUniversity of UlmStarted 2008
The Role of Angiopoietin, Tie-2, and Vascular Endothelial Growth Factor (VEGF) in Sepsis-Induced Multiple Organ Dysfunction Syndrome (MODS) NCT00908635ObservationalUnknown statusChang Gung Memorial HospitalStarted 2008
PROOF: Pancreatitis-associated Risk Of Organ Failure NCT03075605ObservationalCompletedUniversity of PittsburghStarted 2008
The Value of PSP in Predicting Outcome in ICU Surgical Peritonitis Patients NCT01465711ObservationalCompletedUniversity of MagdeburgStarted 2007
Inflammatory Cytokine Variations in Traumatic Injury Responses NCT00593892ObservationalCompletedUniversity of Alabama at BirminghamStarted 2007
Patient Plasma Response and Outcome in Septic Shock With Thrombocytopenia Associated Multiple Organ Failure in Children NCT00118664ObservationalCompletedChildren's Healthcare of AtlantaStarted 2005
Inflammation and the Host Response to Injury (Burns) NCT00257244ObservationalCompletedMassachusetts General HospitalStarted 2004
Inflammation and the Host Response to Injury (Trauma) NCT00257231ObservationalCompletedMassachusetts General HospitalStarted 2003
A Study of HIV and Cytomegalovirus (CMV) in HIV-Infected Patients NCT00001089ObservationalCompletedNational Institute of Allergy and Infectious Diseases (NIAID)

Remimazolam Versus Propofol for Procedural Sedation in Gastrointestinal Endoscopy: A Single-Centre Prospective Observational Comparative Study in a High-Risk Population NCT07362173Status changeActive, not recruiting to CompletedOctober 17, 2026
Remimazolam Versus Propofol for Procedural Sedation in Gastrointestinal Endoscopy: A Single-Centre Prospective Observational Comparative Study in a High-Risk Population NCT07362173Phase changePhase 4 to not statedOctober 17, 2026
Remimazolam Versus Propofol for Procedural Sedation in Gastrointestinal Endoscopy: A Single-Centre Prospective Observational Comparative Study in a High-Risk Population NCT07362173Enrollment change200 to 203October 17, 2026
Remimazolam Versus Propofol for Procedural Sedation in Gastrointestinal Endoscopy: A Single-Centre Prospective Observational Comparative Study in a High-Risk Population NCT07362173Completion date change2026-05-01 to 2026-06-01October 17, 2026

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