Terminated Respiratory Distress Syndrome trials: Trial Insights

Filters: Condition: Respiratory Distress Syndrome Status: Terminated Clear all

128 trials match Source: ClinicalTrials.gov registrations

Trials started per year
Category	Trials
2000	1
2001	3
2003	1
2004	1
2005	5
2006	1
2007	3
2008	3
2009	5
2010	5
2011	5
2012	6
2013	4
2014	2
2015	6
2016	5
2017	3
2018	2
2019	3
2020	38
2021	14
2022	5
2023	3
2024	1

Trials by status
Category	Trials
Terminated	128

Top lead sponsors
Category	Trials
NICHD Neonatal Research Network	5
Windtree Therapeutics	4
Massachusetts General Hospital	3
Bayer	2
Canadian Critical Care Trials Group	2
Chiesi Farmaceutici S.p.A.	2
Hamilton Health Sciences Corporation	2
Hôpital Européen Marseille	2
Johns Hopkins University	2
National Heart, Lung, and Blood Institute (NHLBI)	2

Top conditions
Category	Trials
Respiratory Distress Syndrome	128
COVID-19	35
Acute Lung Injury	18
Coronavirus Infections	13
Respiratory Insufficiency	13
Pneumonia	10
Premature Birth	9
Cytokine Release Syndrome	7
Severe Acute Respiratory Syndrome	7
Pneumonia, Viral	6

Trials

Showing 76 to 100 of 128. Each trial links to its page on Pharma Observatory.

Trial To Assess The Safety And Tolerability Of Lucinactant For Inhalation In Preterm Neonates 26 to 28 Weeks PMA NCT02528318Phase 2TerminatedWindtree TherapeuticsStarted 2015
Study of GSK2862277 in Subjects Undergoing Oesophagectomy Surgery NCT02221037Phase 2TerminatedGlaxoSmithKlineStarted 2015
(S5-SAMU) Randomized Study Comparing the ASV (Adaptative Support Ventilation) to Conventional Ventilation NCT02348047Phase 4TerminatedCentre Hospitalier Intercommunal de Toulon La Seyne sur MerStarted 2015
Treprostinil Sodium Inhalation for Patients At High Risk for ARDS NCT02370095Phase 2TerminatedUniversity of North Carolina, Chapel HillStarted 2015
ASpirin as a Treatment for ARDS (STAR): a Phase 2 Randomised Control Trial NCT02326350Phase 2TerminatedBelfast Health and Social Care TrustStarted 2015
Validation of Digital Chest-X-ray (CXR) to Assess Lung Recruitment in ARDS NCT02081105Not applicableTerminatedHospices Civils de LyonStarted 2014
Trial of an Alternate Mode of Providing Artificial Breaths to Children With Very Severe Pneumonia NCT02167698Not applicableTerminatedPost Graduate Institute of Medical Education and Research, ChandigarhStarted 2014
Acute Lung Injury Ventilator Evaluation (ALIVE) NCT01901354Not applicableTerminatedUniversity of Wisconsin, MadisonStarted 2013
Strain and Blood Inflammatory Markers as Prognostic Tools for ARDS AMIS (ARDS - Markers of Inflammation - Strain) NCT02003326Not applicableTerminatedCentre Hospitalier Universitaire de NiceStarted 2013
Lung and Systemic Inflammation in the Critically Ill Patient NCT01906229ObservationalTerminatedRigshospitalet, DenmarkStarted 2013
Variable Pressure Support Trial NCT01769053Not applicableTerminatedTechnische Universität DresdenStarted 2013
Open Lung Ventilation in ARDS: The PHARLAP Trial NCT01667146Not applicableTerminatedAustralian and New Zealand Intensive Care Research CentreStarted 2012
Hyperoxia and Hypertonic Saline in Septic Shock NCT01722422Not applicableTerminatedUniversity Hospital, AngersStarted 2012
MISurf Versus InSurE. A Comparison of Minimally Invasive Surfactant Application Techniques in Preterm Infants NCT01615016Phase 2TerminatedHamilton Health Sciences CorporationStarted 2012
Clinical Trial of Nebulized Hypertonic Saline to Attenuate Post-Traumatic Acute Lung Injury NCT01667666Phase 1TerminatedDenver Health and Hospital AuthorityStarted 2012
Flow-flow ECCO2-R and 4 ml/kg Tidal Volume vs. 6 ml/kg Tidal Volume to Enhance Protection From VILI in Acute Lung Injury NCT01522599Phase 3TerminatedUniversity of Turin, ItalyStarted 2012
The Effect of High Frequency Oscillation on Biological Markers of Lung Injury NCT01581255ObservationalTerminatedCanadian Critical Care Trials GroupStarted 2012
High Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome (ARDS) NCT01478802Phase 2/3TerminatedUniversity of AthensStarted 2011
Predicting Lung Injury From Transfusion in Patients With Liver Disease NCT01756690ObservationalTerminatedUniversity of Colorado, DenverStarted 2011
Extubation Readiness Study in Very Low Birthweight Infants NCT01471431Not applicableTerminatedUniversity of PennsylvaniaStarted 2011
INR-Triggered Transfusion In GI Bleeders From ER NCT01461889Phase 3TerminatedUniversity of Colorado, DenverStarted 2011
Surfactant Versus Nasal Continuous Positive Airway Pressure (nCPAP) for Respiratory Distress Syndrome in the Newborn ≥ 35 Weeks of Gestation NCT01306240Phase 3TerminatedCentre Hospitalier Universitaire, AmiensStarted 2011
Biomarkers of Lung Injury With Low Tidal Volume Ventilation Compared With Airway Pressure Release Ventilation NCT01038531Not applicableTerminatedBoston Medical CenterStarted 2010
The Effect of Intravenous Lipids on Lung Function in Acute Respiratory Distress Syndrome (ARDS) NCT01096771Phase 2TerminatedMethodist Research Institute, IndianapolisStarted 2010
Effect of Enteral Nutrition Support for Critically Ill Patients NCT01464853Phase 3TerminatedAbbott NutritionStarted 2010

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