Phase 3 Shock, Septic trials: Trial Insights

Filters: Condition: Shock, Septic Phase: Phase 3 Clear all

100 trials match Source: ClinicalTrials.gov registrations

Trials started per year
Category	Trials
2002	1
2003	3
2005	1
2006	2
2007	3
2008	5
2009	4
2010	1
2011	3
2012	4
2013	3
2014	2
2015	2
2016	4
2017	5
2018	8
2019	14
2020	6
2021	6
2022	3
2023	4
2024	5
2025	5
2026	4

Trials by status
Category	Trials
Completed	51
Unknown status	15
Terminated	10
Recruiting	9
Not yet recruiting	6
Withdrawn	4
Active, not recruiting	3
Suspended	2

Top lead sponsors
Category	Trials
Assistance Publique - Hôpitaux de Paris	8
Cairo University	6
Centre Hospitalier Universitaire Dijon	2
Centre Hospitalier Universitaire de Nīmes	2
Centre Hospitalier Universitaire, Amiens	2
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico	2
Frisius Medisch Centrum	2
Hospices Civils de Lyon	2
Kompetenznetz Sepsis	2
Northern Jiangsu People's Hospital	2

Top conditions
Category	Trials
Shock, Septic	100
Sepsis	49
Shock	7
Acute Kidney Injury	4
Critical Illness	4
Neoplasms	3
Adrenal Insufficiency	2
Diabetes Insipidus	2
Hypotension	2
Hypovolemia	2

Trials

Showing 76 to 100 of 100. Each trial links to its page on Pharma Observatory.

Transfusion-requirements in Septic Shock Trial NCT01485315Phase 3CompletedScandinavian Critical Care Trials GroupStarted 2011
Stress Doses of Hydrocortisone on Coagulation Dysfunction in Patients With Septic Shock NCT02266589Phase 3CompletedNanjing PLA General HospitalStarted 2011
The Effect of Ketanserin on the Microcirculation in Sepsis NCT01329887Phase 3CompletedFrisius Medisch CentrumStarted 2011
Effects of Hemoperfusion With a Polymyxin B Membrane in Peritonitis With Septic Shock NCT01222663Phase 3CompletedMeditor SASStarted 2010
Scandinavian Starch for Severe Sepsis/Septic Shock Trial NCT00962156Phase 3CompletedAnders PernerStarted 2009
Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis NCT00832039Phase 3CompletedKompetenznetz SepsisStarted 2009
GCIV as an Adjuvant Therapy for Community-Acquired Severe Sepsis or Septic Shock NCT01315496Phase 3TerminatedGreen Cross CorporationStarted 2009
Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in Sepsis NCT00608322Phase 3CompletedNational Institute of General Medical Sciences (NIGMS)Started 2009
Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial NCT00975793Phase 3Unknown statusBelinda HoweStarted 2008
Volume Replacement With Albumin in Severe Sepsis NCT00707122Phase 3CompletedFondazione IRCCS Ca' Granda, Ospedale Maggiore PoliclinicoStarted 2008
Efficacy and Safety of Drotrecogin Alfa (Activated) in Adult Patients With Septic Shock NCT00604214Phase 3CompletedEli Lilly and CompanyStarted 2008
Activated Protein C and Corticosteroids for Human Septic Shock NCT00625209Phase 3CompletedUniversity of VersaillesStarted 2008
Efficacy and Safety of Resatorvid in Patients With Sepsis-induced Cardiovascular and Respiratory Failure NCT00633477Phase 3TerminatedTakedaStarted 2008
Comparison of Two Antibiotic Regimen (Meropenem Versus Meropenem+Moxifloxacin)in the Treatment of Severe Sepsis and Septic Shock NCT00534287Phase 3CompletedKompetenznetz SepsisStarted 2007
Clarithromycin as Immunomodulator for the Management of Sepsis NCT01223690Phase 3CompletedUniversity of AthensStarted 2007
The Effect of Nitroglycerine on Microcirculatory Abnormalities During Sepsis NCT00493415Phase 3CompletedFrisius Medisch CentrumStarted 2007
ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis NCT00334828Phase 3CompletedEisai Inc.Started 2006
Combination of Corticotherapy and Intensive Insulin Therapy for Septic Shock NCT00320099Phase 3CompletedUniversity of VersaillesStarted 2006
Efficacy & Safety of Resatorvid in Adults With Severe Sepsis NCT00143611Phase 3CompletedTakedaStarted 2005
Dopamine and Norepinephrine in Shock Patients NCT00314704Phase 3CompletedSepsis Occurrence in Acutely Ill PatientsStarted 2003
Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial) NCT00135473Phase 3CompletedSepNet - Critical Care Trials GroupStarted 2003
Dopamine Versus Norepinephrine for the Treatment of Vasopressor Dependent Septic Shock NCT00604019Phase 3CompletedRush University Medical CenterStarted 2003
Corticosteroid Therapy of Septic Shock - Corticus NCT00147004Phase 3CompletedHadassah Medical OrganizationStarted 2002
Ibuprofen in Sepsis Study NCT00000574Phase 3CompletedVanderbilt UniversityStarted 1990
Effects of Fludrocortisone on Norepinephrine-mean Arterial Pressure Dose-response in Septic Shock NCT02069288Phase 3WithdrawnRennes University Hospital

Comparative Efficacy and Safety of Propofol-Ketamine Combination Versus Propofol Monotherapy in Geriatric Patients Under Invasive Ventilation NCT07530146Status changeRecruiting to Active, not recruitingOctober 17, 2026

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