Completed Systemic Inflammatory Response Syndrome trials: Trial Insights

Filters: Condition: Systemic Inflammatory Response Syndrome Status: Completed Clear all

108 trials match Source: ClinicalTrials.gov registrations

Trials started per year
Category	Trials
2001	2
2003	3
2004	2
2005	1
2006	4
2007	6
2008	4
2009	6
2010	3
2011	3
2012	5
2013	6
2014	9
2015	6
2016	8
2017	9
2018	5
2019	3
2020	5
2021	3
2022	4
2023	5
2024	3
2026	1

Trials by status
Category	Trials
Completed	108

Top lead sponsors
Category	Trials
University of Ulm	4
Rigshospitalet, Denmark	3
Ain Shams University	2
Amsterdam UMC, location VUmc	2
CalciMedica, Inc.	2
Charles University, Czech Republic	2
Chinese PLA General Hospital	2
Christian Hassager	2
Hvidovre University Hospital	2
Immunexpress	2

Top conditions
Category	Trials
Systemic Inflammatory Response Syndrome	108
Sepsis	49
Inflammation	21
Infections	16
Shock, Septic	14
Critical Illness	10
Pathologic Processes	7
Acute Kidney Injury	6
Shock	6
Multiple Organ Failure	5

Trials

Showing 51 to 75 of 108. Each trial links to its page on Pharma Observatory.

Optimal Oxygenation in the Intensive Care Unit NCT02321072Phase 4CompletedAmsterdam UMC, location VUmcStarted 2015
Platelet REactivity in Sepsis Syndrome (PRESS) NCT02562261ObservationalCompletedCharalambos .A. GogosStarted 2015
PPV to Guide Fluid Management in the PICU NCT02308371Not applicableCompletedUniversity of North Carolina, Chapel HillStarted 2014
MicroRNA Diagnostics in Subarachnoid Hemorrhage 2 NCT02320539ObservationalCompletedRigshospitalet, DenmarkStarted 2014
Effect of TEAS on the Incidence Rate of SIRS in Patients Undergoing Abdominal Surgery NCT02193477Not applicableCompletedAir Force Military Medical University, ChinaStarted 2014
Effect of Education on Resident Physician Knowledge of Sepsis NCT02927054Not applicableCompletedUniversity of UtahStarted 2014
VENUS: Septic Gene Expression Using SeptiCyte NCT02127502ObservationalCompletedImmunexpressStarted 2014
Studying Complement Inhibition in Early, Newly Developing Septic Organ Dysfunction NCT02246595Phase 2CompletedInflaRx GmbHStarted 2014
The Importance of Albumin Infusion Rate for Plasma Volume Expansion Following Major Abdominal Surgery NCT02728921Phase 4CompletedRegion SkaneStarted 2014
Influence of Age, Sepsis and SLCO1A2 Polymorphisms on Rocuronium Pharmacokinetics NCT02399397Phase 4CompletedUniversidade Estadual Paulista Júlio de Mesquita FilhoStarted 2014
The Association Between Preoperative Sepsis and the Mortality After Hip Fracture Surgery NCT03201679ObservationalCompletedBispebjerg HospitalStarted 2014
Systemic Inflammatory Response Syndrome (SIRS) in Patients Undergoing Major Procedures in Oral and Maxillofacial Surgery NCT01921049ObservationalCompletedUniversity of CologneStarted 2013
Effects of Transvenous Vagus Nerve Stimulation on Immune Response: a Pilot Study NCT01944228Phase 1CompletedMedtronic Cardiac Rhythm and Heart FailureStarted 2013
Endothelial Microparticles as a Biomarker for Diagnosis and Prognosis in Early Sepsis NCT01998139ObservationalCompletedWeill Medical College of Cornell UniversityStarted 2013
Genotypes and Phenotypes in Pediatric SIRS and Sepsis NCT02728401ObservationalCompletedSeattle Children's HospitalStarted 2013
The Effect of Protein and Resistance Training on Muscle Mass in Acutely Ill Old Medical Patients NCT02077491Not applicableCompletedHvidovre University HospitalStarted 2013
Effects of Free Fatty Acids and 3-hydroxybutyrate on Protein, Glucose, Lipid Metabolism and Intracellular Signals. NCT01752348Not applicableCompletedUniversity of AarhusStarted 2013
IL8 Monitoring and Its Correlation With 251-gene Polymorphism NCT01708759ObservationalCompletedTanta UniversityStarted 2012
Autonomic Nervous Activity During the Systemic Inflammatory Response in Trained and Untrained Healthy Volunteers NCT01592526Phase 1CompletedRigshospitalet, DenmarkStarted 2012
Inflammatory Response in Aortic Valve Replacement NCT02324140ObservationalCompletedInsel Gruppe AG, University Hospital BernStarted 2012
Pharmacokinetic Study of Ceftaroline Fosamil/Avibactam in Adults With Augmented Renal Clearance NCT01624246Phase 1CompletedForest LaboratoriesStarted 2012
Using Biomarkers to Optimize Antibiotic Strategies in Sepsis NCT02207114Not applicableCompletedUniversity of PennsylvaniaStarted 2012
Vitamin D and Critically Ill Patients NCT01636232ObservationalCompletedChinese PLA General HospitalStarted 2011
Corticosteroid Prophylaxis on the Cardiopulmonary Bypass-Induced Systemic Inflammatory Response NCT01296074Not applicableCompletedBeijing Anzhen HospitalStarted 2011
IMproved PREdiction of Severe Sepsis in the Emergency Department NCT01392508ObservationalCompletedAxis Shield Diagnostics LtdStarted 2011

8 more trials match. See them on Pharma Observatory

Implementation of Timely Management of Sepsis and Septic Shock Protocol in the Emergency Department and Intensive Care Unit: A Quality Improvement Project at AFHJ NCT07460024Status changeNot yet recruiting to CompletedOctober 18, 2026
Implementation of Timely Management of Sepsis and Septic Shock Protocol in the Emergency Department and Intensive Care Unit: A Quality Improvement Project at AFHJ NCT07460024Completion date change2026-11-30 to 2026-10-03October 18, 2026

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