Completed Iron Overload trials: Trial Insights

Filters: Condition: Iron Overload Status: Completed Clear all

101 trials match Source: ClinicalTrials.gov registrations

Trials started per year
Category	Trials
2000	2
2001	1
2002	2
2003	7
2004	2
2005	5
2006	3
2007	10
2008	11
2009	7
2010	5
2011	6
2012	4
2013	6
2014	4
2015	3
2016	2
2018	3
2019	5
2020	3
2022	3
2024	3

Trials by status
Category	Trials
Completed	101

Top lead sponsors
Category	Trials
Novartis Pharmaceuticals	30
Rennes University Hospital	6
ApoPharma	4
HaEmek Medical Center, Israel	4
St. Jude Children's Research Hospital	3
University of Wisconsin, Madison	3
Children's Hospital Los Angeles	2
Hangzhou Zede Pharma-Tech Co., Ltd.	2
Lipomed	2
National Heart, Lung, and Blood Institute (NHLBI)	2

Top conditions
Category	Trials
Iron Overload	101
Thalassemia	30
beta-Thalassemia	22
Hemochromatosis	14
Anemia, Sickle Cell	13
Myelodysplastic Syndromes	11
Hemosiderosis	7
Anemia	6
Hematologic Diseases	4
Anemia, Aplastic	3

Trials

Showing 51 to 75 of 101. Each trial links to its page on Pharma Observatory.

Safety and Pharmacokinetic Study of Escalating Multiple Doses of an Iron Chelator in Patients With Iron Overload NCT01039636Phase 1CompletedFerroKin BioSciences, Inc.Started 2009
Palatability and Tolerability of Deferasirox Taken With Meals, With Different Liquids or Crushed and Added to Food NCT00845871Phase 4CompletedNovartis PharmaceuticalsStarted 2009
Evaluation of Phlebotomy as a Treatment for Non-alcoholic Fatty Liver Disease NCT00641524Not applicableCompletedUniversity of Western Ontario, CanadaStarted 2009
Iron Overload and Growth Velocity in Thalassemia and Sickle Cell Anemia NCT00972231ObservationalCompletedHaEmek Medical Center, IsraelStarted 2009
Iron Overload in Patients Undergoing Donor Stem Cell Transplant NCT00888316ObservationalCompletedMasonic Cancer Center, University of MinnesotaStarted 2008
Open-Label Single-Arm Pilot Study in Adult Allogeneic Hematopoietic Stem Cell Transplant Recipients With Transfusional Iron Overload NCT01335035Phase 4CompletedNovartis PharmaceuticalsStarted 2008
Efficacy and Safety of Deferasirox in Non-transfusion Dependent Thalassemia Patients With Iron Overload and a One Year Open-label Extension Study NCT00873041Phase 2CompletedNovartis PharmaceuticalsStarted 2008
Changes in Pituitary Iron and Volume With Deferasirox NCT01376622ObservationalCompletedChildren's Hospital Los AngelesStarted 2008
Effects of Taking Prenatal Vitamin-mineral Supplements During Lactation on Iron Status and Markers of Oxidation NCT01047098Not applicableCompletedUniversity of California, DavisStarted 2008
Clinical and Laboratory Assessment of Iron Overload in Sickle Cell Anemia and Sickle Cell Thalassemia NCT00512564ObservationalCompletedHaEmek Medical Center, IsraelStarted 2008
Bone Status on Patients With Genetic Hemochromatosis: a 3 Years Descriptive and Evolutionary Study NCT01556360ObservationalCompletedRennes University HospitalStarted 2008
Oral Nifedipine to Treat Iron Overload NCT00712738Phase 1CompletedNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Started 2008
Observational Study of Iron Overload in Stem Cell Transplantation NCT00954720ObservationalCompletedDana-Farber Cancer InstituteStarted 2008
Efficacy and Safety of Oral Deferasirox (20 mg/kg/d) in Pts 3 to 6 Months After Allogeneic Hematopoietic Cell Transplantation Who Present With Iron Overload NCT00654589Phase 4CompletedNovartis PharmaceuticalsStarted 2008
MRI Evaluation of Iron Overload in the Heart, Liver and Pancreas in Patients Receiving Multiple Blood Transfusions. NCT00629291ObservationalCompletedSheba Medical CenterStarted 2008
Evaluating the Efficacy of Deferasirox in Transfusion Dependent Chronic Anaemias (Myelodysplastic Syndrome, Beta-thalassaemia Patients) With Chronic Iron Overload NCT00564941Phase 4CompletedNovartis PharmaceuticalsStarted 2007
Evaluating Use of Deferasirox as Compared to Deferoxamine in Treating Cardiac Iron Overload NCT00600938Phase 2CompletedNovartis PharmaceuticalsStarted 2007
Efficacy and Safety of Deferasirox in Patients With Chronic Anemia and Transfusional Hemosiderosis NCT00631163Phase 2CompletedNovartis PharmaceuticalsStarted 2007
Iron Overload Assesment in Sickle Cell Anemia and Sickle Cell Thalassemia NCT00512226Not applicableCompletedHaEmek Medical Center, IsraelStarted 2007
Combined Chelation Therapy in Patients With Transfusion Dependent Thalassemia and Iron Overload NCT00901199Phase 2CompletedElliott VichinskyStarted 2007
Safety and Efficacy of Ferriprox™ (Deferiprone) Oral Solution in Iron Overloaded Pediatric Patients NCT00529152Phase 3CompletedApoPharmaStarted 2007
ENTRUST, a 5 Year Surveillance of Children Aged 2 to <6 Years With Transfusional Iron Overload Treated With Deferasirox NCT00466063ObservationalCompletedNovartis PharmaceuticalsStarted 2007
Efficacy and Safety of Deferasirox in Patients With Myelodysplastic Syndrome and Transfusion-dependent Iron Overload NCT00481143Phase 4CompletedNovartis PharmaceuticalsStarted 2007
Safety and Efficacy of Iron Reduction by Phlebotomy NCT00689182Phase 2CompletedAndrea KewStarted 2007
Iron Overload in Stem Cell Transplant Recipients NCT00806715ObservationalCompletedBoston Children's HospitalStarted 2007

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