Clinical trials
alpha 1-Antitrypsin Deficiency trials
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
138 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 1 |
| 2001 | 2 |
| 2002 | 1 |
| 2003 | 2 |
| 2004 | 2 |
| 2005 | 2 |
| 2006 | 6 |
| 2007 | 4 |
| 2008 | 2 |
| 2009 | 1 |
| 2010 | 7 |
| 2011 | 1 |
| 2012 | 5 |
| 2013 | 5 |
| 2014 | 5 |
| 2015 | 7 |
| 2016 | 8 |
| 2017 | 7 |
| 2018 | 8 |
| 2019 | 9 |
| 2020 | 4 |
| 2021 | 4 |
| 2022 | 5 |
| 2023 | 7 |
| 2024 | 9 |
| 2025 | 8 |
| 2026 | 9 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 66 |
| Recruiting | 19 |
| Terminated | 18 |
| Unknown status | 10 |
| Withdrawn | 8 |
| Active, not recruiting | 7 |
| Not yet recruiting | 5 |
| Enrolling by invitation | 3 |
| No longer available | 1 |
| Suspended | 1 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Grifols Therapeutics LLC | 12 |
| Baxalta now part of Shire | 8 |
| University of Florida | 6 |
| Arrowhead Pharmaceuticals | 5 |
| Takeda | 5 |
| Vertex Pharmaceuticals Incorporated | 5 |
| CSL Behring | 4 |
| Columbia University | 4 |
| Kamada, Ltd. | 4 |
| Medical University of South Carolina | 4 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| alpha 1-Antitrypsin Deficiency | 138 |
| Pulmonary Disease, Chronic Obstructive | 30 |
| Emphysema | 29 |
| Lung Diseases | 10 |
| Genetic Diseases, Inborn | 8 |
| Cystic Fibrosis | 7 |
| Pulmonary Emphysema | 7 |
| Liver Diseases | 5 |
| Pulmonary Fibrosis | 5 |
| Bronchiectasis | 4 |
Trials
Showing 26 to 50 of 138. Each trial links to its page on Pharma Observatory.
38 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
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