Clinical trials
Substance-Related Disorders trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
1,581 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 5 |
| 2001 | 15 |
| 2002 | 13 |
| 2003 | 32 |
| 2004 | 50 |
| 2005 | 49 |
| 2006 | 49 |
| 2007 | 41 |
| 2008 | 50 |
| 2009 | 63 |
| 2010 | 64 |
| 2011 | 60 |
| 2012 | 59 |
| 2013 | 52 |
| 2014 | 52 |
| 2015 | 59 |
| 2016 | 44 |
| 2017 | 74 |
| 2018 | 56 |
| 2019 | 66 |
| 2020 | 69 |
| 2021 | 70 |
| 2022 | 76 |
| 2023 | 77 |
| 2024 | 75 |
| 2025 | 80 |
| 2026 | 93 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 1,115 |
| Recruiting | 170 |
| Unknown status | 73 |
| Active, not recruiting | 61 |
| Terminated | 51 |
| Not yet recruiting | 45 |
| Withdrawn | 43 |
| Enrolling by invitation | 16 |
| Suspended | 7 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| National Institute on Drug Abuse (NIDA) | 92 |
| Yale University | 61 |
| VA Office of Research and Development | 60 |
| Medical University of South Carolina | 46 |
| University of California, Los Angeles | 46 |
| Johns Hopkins University | 38 |
| University of Washington | 27 |
| University of California, San Francisco | 25 |
| University of Chicago | 25 |
| Massachusetts General Hospital | 24 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Substance-Related Disorders | 1,581 |
| Opioid-Related Disorders | 200 |
| Alcoholism | 148 |
| Stress Disorders, Post-Traumatic | 101 |
| Anxiety Disorders | 79 |
| Cocaine-Related Disorders | 75 |
| Acquired Immunodeficiency Syndrome | 67 |
| Mental Disorders | 67 |
| HIV Infections | 66 |
| Marijuana Abuse | 47 |
Trials
Showing 76 to 100 of 1,581. Each trial links to its page on Pharma Observatory.
1,481 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.