Clinical trials
Phase 4 trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
10,671 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 53 |
| 2001 | 84 |
| 2002 | 156 |
| 2003 | 260 |
| 2004 | 329 |
| 2005 | 372 |
| 2006 | 456 |
| 2007 | 438 |
| 2008 | 500 |
| 2009 | 494 |
| 2010 | 455 |
| 2011 | 421 |
| 2012 | 417 |
| 2013 | 440 |
| 2014 | 428 |
| 2015 | 413 |
| 2016 | 462 |
| 2017 | 508 |
| 2018 | 494 |
| 2019 | 507 |
| 2020 | 440 |
| 2021 | 458 |
| 2022 | 396 |
| 2023 | 364 |
| 2024 | 357 |
| 2025 | 343 |
| 2026 | 406 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 6,662 |
| Terminated | 1,403 |
| Recruiting | 877 |
| Withdrawn | 589 |
| Unknown status | 555 |
| Active, not recruiting | 270 |
| Not yet recruiting | 193 |
| Enrolling by invitation | 93 |
| Suspended | 29 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Massachusetts General Hospital | 209 |
| Mayo Clinic | 188 |
| University of California, San Francisco | 165 |
| Emory University | 143 |
| Duke University | 142 |
| GlaxoSmithKline | 112 |
| NYU Langone Health | 108 |
| University of Texas Southwestern Medical Center | 105 |
| The University of Texas Health Science Center, Houston | 99 |
| Stanford University | 97 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Postoperative Pain | 345 |
| Pain | 341 |
| Diabetes Mellitus, Type 2 | 294 |
| Diabetes Mellitus | 215 |
| Obesity | 198 |
| Schizophrenia | 192 |
| Major Depressive Disorder | 185 |
| Hypertension | 179 |
| HIV Infections | 156 |
| Bipolar Disorder | 155 |
Trials
Showing 26 to 50 of 10,671. Each trial links to its page on Pharma Observatory.
10,571 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.