Clinical trials
Phase 1 trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
27,435 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 199 |
| 2001 | 219 |
| 2002 | 281 |
| 2003 | 361 |
| 2004 | 511 |
| 2005 | 614 |
| 2006 | 755 |
| 2007 | 898 |
| 2008 | 1,008 |
| 2009 | 1,085 |
| 2010 | 1,104 |
| 2011 | 1,131 |
| 2012 | 1,051 |
| 2013 | 1,131 |
| 2014 | 1,253 |
| 2015 | 1,131 |
| 2016 | 1,165 |
| 2017 | 1,224 |
| 2018 | 1,286 |
| 2019 | 1,314 |
| 2020 | 1,258 |
| 2021 | 1,356 |
| 2022 | 1,286 |
| 2023 | 1,225 |
| 2024 | 1,239 |
| 2025 | 1,179 |
| 2026 | 1,113 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 18,326 |
| Terminated | 3,158 |
| Recruiting | 2,542 |
| Active, not recruiting | 1,340 |
| Withdrawn | 780 |
| Unknown status | 734 |
| Not yet recruiting | 348 |
| Suspended | 133 |
| Enrolling by invitation | 74 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| National Cancer Institute (NCI) | 932 |
| National Institute of Allergy and Infectious Diseases (NIAID) | 767 |
| Pfizer | 656 |
| M.D. Anderson Cancer Center | 514 |
| Eli Lilly and Company | 502 |
| GlaxoSmithKline | 413 |
| AstraZeneca | 404 |
| Bristol-Myers Squibb | 364 |
| Mayo Clinic | 361 |
| Memorial Sloan Kettering Cancer Center | 360 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Neoplasms | 1,388 |
| Breast Neoplasms | 963 |
| Carcinoma, Non-Small-Cell Lung | 896 |
| Leukemia, Myeloid, Acute | 767 |
| Neoplasm Metastasis | 697 |
| HIV Infections | 669 |
| Melanoma | 632 |
| Lymphoma | 581 |
| Prostatic Neoplasms | 568 |
| Multiple Myeloma | 552 |
Trials
Showing 51 to 75 of 27,435. Each trial links to its page on Pharma Observatory.
27,335 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.