Clinical trials
Homozygous Familial Hypercholesterolemia trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
36 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2003 | 2 |
| 2006 | 1 |
| 2007 | 3 |
| 2008 | 1 |
| 2009 | 1 |
| 2010 | 1 |
| 2011 | 1 |
| 2012 | 2 |
| 2014 | 1 |
| 2015 | 1 |
| 2016 | 4 |
| 2017 | 2 |
| 2018 | 3 |
| 2019 | 4 |
| 2020 | 1 |
| 2021 | 1 |
| 2022 | 1 |
| 2023 | 1 |
| 2024 | 1 |
| 2025 | 2 |
| 2026 | 2 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 23 |
| Recruiting | 7 |
| Terminated | 3 |
| Unknown status | 2 |
| Active, not recruiting | 1 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Regeneron Pharmaceuticals | 5 |
| Kastle Therapeutics, LLC | 4 |
| Novartis Pharmaceuticals | 4 |
| Aegerion Pharmaceuticals, Inc. | 3 |
| Amgen | 3 |
| Arrowhead Pharmaceuticals | 3 |
| REGENXBIO Inc. | 3 |
| University of Pennsylvania | 2 |
| Amryt Pharma | 1 |
| CRISPR Therapeutics AG | 1 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Homozygous Familial Hypercholesterolemia | 36 |
| Hyperlipoproteinemia Type II | 18 |
| Hypercholesterolemia | 11 |
| Metabolic Diseases | 8 |
| Genetic Diseases, Inborn | 7 |
| Dyslipidemias | 6 |
| Hyperlipidemias | 5 |
| Lipid Metabolism Disorders | 5 |
| Cardiovascular Diseases | 4 |
| Hyperlipoproteinemias | 4 |
Trials
Showing 1 to 25 of 36. Each trial links to its page on Pharma Observatory.
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
No changes to these trials in the last 7 days.
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