Clinical trials
Phase 1 Alzheimer Disease trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
298 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 1 |
| 2001 | 1 |
| 2003 | 2 |
| 2004 | 4 |
| 2005 | 3 |
| 2006 | 5 |
| 2007 | 14 |
| 2008 | 15 |
| 2009 | 27 |
| 2010 | 19 |
| 2011 | 8 |
| 2012 | 11 |
| 2013 | 12 |
| 2014 | 11 |
| 2015 | 17 |
| 2016 | 17 |
| 2017 | 11 |
| 2018 | 12 |
| 2019 | 16 |
| 2020 | 13 |
| 2021 | 17 |
| 2022 | 15 |
| 2023 | 13 |
| 2024 | 13 |
| 2025 | 6 |
| 2026 | 12 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 215 |
| Terminated | 32 |
| Recruiting | 22 |
| Active, not recruiting | 12 |
| Not yet recruiting | 7 |
| Unknown status | 6 |
| Withdrawn | 4 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Eli Lilly and Company | 19 |
| Institute for Neurodegenerative Disorders | 18 |
| Pfizer | 17 |
| Avid Radiopharmaceuticals | 12 |
| Bristol-Myers Squibb | 10 |
| Molecular NeuroImaging | 9 |
| Eisai Inc. | 6 |
| Merck Sharp & Dohme LLC | 6 |
| Wyeth is now a wholly owned subsidiary of Pfizer | 6 |
| AbbVie | 5 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Alzheimer Disease | 298 |
| Cognitive Dysfunction | 36 |
| Dementia | 26 |
| Parkinson Disease | 12 |
| Huntington Disease | 9 |
| Supranuclear Palsy, Progressive | 7 |
| Central Nervous System Diseases | 6 |
| Neurodegenerative Diseases | 6 |
| Tauopathies | 6 |
| Multiple Sclerosis | 4 |
Trials
Showing 1 to 25 of 298. Each trial links to its page on Pharma Observatory.
198 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
No changes to these trials in the last 7 days.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.