Clinical trials
Completed Amyotrophic Lateral Sclerosis trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
235 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 1 |
| 2001 | 4 |
| 2002 | 4 |
| 2003 | 4 |
| 2004 | 2 |
| 2005 | 6 |
| 2006 | 8 |
| 2007 | 9 |
| 2008 | 12 |
| 2009 | 8 |
| 2010 | 8 |
| 2011 | 13 |
| 2012 | 10 |
| 2013 | 16 |
| 2014 | 4 |
| 2015 | 13 |
| 2016 | 18 |
| 2017 | 14 |
| 2018 | 13 |
| 2019 | 12 |
| 2020 | 15 |
| 2021 | 14 |
| 2022 | 10 |
| 2023 | 6 |
| 2024 | 5 |
| 2025 | 1 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 235 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Massachusetts General Hospital | 15 |
| National Institute of Neurological Disorders and Stroke (NINDS) | 8 |
| Cytokinetics | 7 |
| Knopp Biosciences | 7 |
| Merit E. Cudkowicz, MD | 7 |
| Mayo Clinic | 6 |
| University of Michigan | 6 |
| Columbia University | 5 |
| Duke University | 5 |
| Johns Hopkins University | 5 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Amyotrophic Lateral Sclerosis | 235 |
| Motor Neuron Disease | 40 |
| Neurodegenerative Diseases | 13 |
| Parkinson Disease | 12 |
| Neuromuscular Diseases | 10 |
| Multiple Sclerosis | 8 |
| Muscular Atrophy, Spinal | 7 |
| Nervous System Diseases | 7 |
| Spinal Cord Injuries | 7 |
| Alzheimer Disease | 6 |
Trials
Showing 1 to 25 of 235. Each trial links to its page on Pharma Observatory.
135 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
No changes to these trials in the last 7 days.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.