Clinical trials
Major Depressive Disorder trials
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
2,964 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 10 |
| 2001 | 21 |
| 2002 | 40 |
| 2003 | 37 |
| 2004 | 59 |
| 2005 | 76 |
| 2006 | 88 |
| 2007 | 97 |
| 2008 | 103 |
| 2009 | 96 |
| 2010 | 111 |
| 2011 | 142 |
| 2012 | 123 |
| 2013 | 96 |
| 2014 | 103 |
| 2015 | 110 |
| 2016 | 126 |
| 2017 | 107 |
| 2018 | 107 |
| 2019 | 135 |
| 2020 | 128 |
| 2021 | 175 |
| 2022 | 152 |
| 2023 | 151 |
| 2024 | 163 |
| 2025 | 177 |
| 2026 | 174 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 1,789 |
| Recruiting | 337 |
| Unknown status | 316 |
| Terminated | 187 |
| Not yet recruiting | 125 |
| Withdrawn | 93 |
| Active, not recruiting | 73 |
| Enrolling by invitation | 27 |
| Suspended | 15 |
| No longer available | 1 |
| Approved for marketing | 1 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Massachusetts General Hospital | 85 |
| National Institute of Mental Health (NIMH) | 65 |
| Eli Lilly and Company | 57 |
| New York State Psychiatric Institute | 50 |
| Centre for Addiction and Mental Health | 48 |
| Janssen Research & Development, LLC | 38 |
| Shanghai Mental Health Center | 38 |
| Stanford University | 38 |
| University of California, Los Angeles | 37 |
| Otsuka Pharmaceutical Development & Commercialization, Inc. | 36 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Major Depressive Disorder | 2,964 |
| Bipolar Disorder | 247 |
| Depressive Disorder | 215 |
| Depressive Disorder, Treatment-Resistant | 171 |
| Anxiety Disorders | 137 |
| Mood Disorders | 123 |
| Schizophrenia | 118 |
| Stress Disorders, Post-Traumatic | 85 |
| Mental Disorders | 78 |
| Psychotic Disorders | 70 |
Trials
Showing 1 to 25 of 2,964. Each trial links to its page on Pharma Observatory.
2,864 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
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