Clinical trials
Phase 3 Major Depressive Disorder trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
237 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2001 | 1 |
| 2002 | 8 |
| 2003 | 8 |
| 2004 | 10 |
| 2005 | 11 |
| 2006 | 21 |
| 2007 | 7 |
| 2008 | 10 |
| 2009 | 9 |
| 2010 | 16 |
| 2011 | 20 |
| 2012 | 9 |
| 2013 | 9 |
| 2014 | 7 |
| 2015 | 6 |
| 2016 | 8 |
| 2017 | 5 |
| 2018 | 9 |
| 2019 | 6 |
| 2020 | 8 |
| 2021 | 9 |
| 2022 | 5 |
| 2023 | 6 |
| 2024 | 8 |
| 2025 | 11 |
| 2026 | 9 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 178 |
| Terminated | 24 |
| Recruiting | 20 |
| Active, not recruiting | 6 |
| Withdrawn | 5 |
| Unknown status | 2 |
| Suspended | 1 |
| Enrolling by invitation | 1 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Forest Laboratories | 18 |
| Otsuka Pharmaceutical Development & Commercialization, Inc. | 17 |
| Eli Lilly and Company | 14 |
| Janssen Research & Development, LLC | 13 |
| AstraZeneca | 9 |
| H. Lundbeck A/S | 8 |
| Naurex, Inc, an affiliate of Allergan plc | 8 |
| Pfizer | 8 |
| Alkermes, Inc. | 7 |
| Sanofi | 7 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Major Depressive Disorder | 237 |
| Depressive Disorder | 24 |
| Mental Disorders | 9 |
| Mood Disorders | 9 |
| Psychotic Disorders | 7 |
| Anhedonia | 4 |
| Bipolar Disorder | 4 |
| Depressive Disorder, Treatment-Resistant | 4 |
| Anxiety Disorders | 3 |
| Dysthymic Disorder | 3 |
Trials
Showing 1 to 25 of 237. Each trial links to its page on Pharma Observatory.
137 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
Go deeper on Pharma Observatory
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