Clinical trials
Completed Phase 3 Major Depressive Disorder trials
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
289 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2001 | 6 |
| 2002 | 15 |
| 2003 | 8 |
| 2004 | 14 |
| 2005 | 20 |
| 2006 | 27 |
| 2007 | 10 |
| 2008 | 14 |
| 2009 | 17 |
| 2010 | 18 |
| 2011 | 29 |
| 2012 | 16 |
| 2013 | 11 |
| 2014 | 12 |
| 2015 | 12 |
| 2016 | 8 |
| 2017 | 6 |
| 2018 | 7 |
| 2019 | 6 |
| 2020 | 10 |
| 2021 | 6 |
| 2022 | 4 |
| 2023 | 3 |
| 2024 | 2 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 289 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Eli Lilly and Company | 19 |
| Forest Laboratories | 18 |
| H. Lundbeck A/S | 18 |
| Wyeth is now a wholly owned subsidiary of Pfizer | 18 |
| AstraZeneca | 14 |
| Otsuka Pharmaceutical Development & Commercialization, Inc. | 13 |
| Takeda | 12 |
| Sanofi | 11 |
| Merck Sharp & Dohme LLC | 9 |
| Pfizer | 9 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Major Depressive Disorder | 289 |
| Depressive Disorder | 30 |
| Mental Disorders | 11 |
| Mood Disorders | 11 |
| Psychotic Disorders | 11 |
| Bipolar Disorder | 7 |
| Anxiety Disorders | 5 |
| Depressive Disorder, Treatment-Resistant | 5 |
| Sleep Initiation and Maintenance Disorders | 5 |
| Recurrence | 4 |
Trials
Showing 1 to 25 of 289. Each trial links to its page on Pharma Observatory.
189 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
No changes to these trials in the last 7 days.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.