Clinical trials
Phase 2 Depressive Disorder trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
48 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 1 |
| 2001 | 1 |
| 2003 | 3 |
| 2004 | 1 |
| 2006 | 3 |
| 2008 | 2 |
| 2009 | 1 |
| 2012 | 1 |
| 2013 | 2 |
| 2014 | 1 |
| 2015 | 1 |
| 2017 | 3 |
| 2018 | 2 |
| 2019 | 2 |
| 2020 | 2 |
| 2021 | 1 |
| 2022 | 3 |
| 2023 | 4 |
| 2024 | 5 |
| 2025 | 3 |
| 2026 | 2 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 35 |
| Recruiting | 6 |
| Terminated | 4 |
| Enrolling by invitation | 2 |
| Active, not recruiting | 1 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| National Institute of Mental Health (NIMH) | 8 |
| Vanderbilt University Medical Center | 3 |
| Clexio Biosciences Ltd. | 2 |
| Marinus Pharmaceuticals | 2 |
| Otsuka Pharmaceutical Development & Commercialization, Inc. | 2 |
| Seaport Therapeutics | 2 |
| University of California, San Diego | 2 |
| Yale University | 2 |
| Alan Davis | 1 |
| AstraZeneca | 1 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Depressive Disorder | 48 |
| Major Depressive Disorder | 29 |
| Mood Disorders | 16 |
| Mental Disorders | 7 |
| Depressive Disorder, Treatment-Resistant | 6 |
| Bipolar Disorder | 5 |
| Anxiety Disorders | 4 |
| Depression, Postpartum | 2 |
| Pregnancy Complications | 2 |
| Puerperal Disorders | 2 |
Trials
Showing 1 to 25 of 48. Each trial links to its page on Pharma Observatory.
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
No changes to these trials in the last 7 days.
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