Clinical trials
Down Syndrome trials
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
432 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 2 |
| 2001 | 2 |
| 2002 | 1 |
| 2003 | 1 |
| 2004 | 2 |
| 2005 | 4 |
| 2006 | 6 |
| 2007 | 5 |
| 2008 | 8 |
| 2009 | 13 |
| 2010 | 11 |
| 2011 | 6 |
| 2012 | 16 |
| 2013 | 19 |
| 2014 | 13 |
| 2015 | 18 |
| 2016 | 13 |
| 2017 | 14 |
| 2018 | 25 |
| 2019 | 24 |
| 2020 | 17 |
| 2021 | 33 |
| 2022 | 19 |
| 2023 | 40 |
| 2024 | 33 |
| 2025 | 49 |
| 2026 | 33 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 246 |
| Recruiting | 74 |
| Unknown status | 45 |
| Terminated | 23 |
| Not yet recruiting | 18 |
| Active, not recruiting | 15 |
| Enrolling by invitation | 6 |
| Withdrawn | 5 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Riphah International University | 48 |
| Cairo University | 12 |
| University of Colorado, Denver | 12 |
| Institut Jerome Lejeune | 10 |
| Natera, Inc. | 8 |
| Sequenom, Inc. | 8 |
| University of Kansas Medical Center | 8 |
| University of Sao Paulo | 8 |
| Children's Hospital Medical Center, Cincinnati | 7 |
| Hoffmann-La Roche | 7 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Down Syndrome | 432 |
| Alzheimer Disease | 30 |
| Sleep Apnea, Obstructive | 27 |
| Trisomy 18 Syndrome | 27 |
| Trisomy 13 Syndrome | 24 |
| Cerebral Palsy | 18 |
| Intellectual Disability | 18 |
| Aneuploidy | 15 |
| Turner Syndrome | 14 |
| Autism Spectrum Disorder | 13 |
Trials
Showing 1 to 25 of 432. Each trial links to its page on Pharma Observatory.
332 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
Go deeper on Pharma Observatory
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