Clinical trials
Phase 4 Pain trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
341 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2001 | 4 |
| 2002 | 1 |
| 2003 | 2 |
| 2004 | 7 |
| 2005 | 2 |
| 2006 | 11 |
| 2007 | 13 |
| 2008 | 17 |
| 2009 | 14 |
| 2010 | 17 |
| 2011 | 22 |
| 2012 | 20 |
| 2013 | 19 |
| 2014 | 33 |
| 2015 | 22 |
| 2016 | 22 |
| 2017 | 20 |
| 2018 | 15 |
| 2019 | 21 |
| 2020 | 8 |
| 2021 | 16 |
| 2022 | 5 |
| 2023 | 9 |
| 2024 | 8 |
| 2025 | 4 |
| 2026 | 5 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 219 |
| Terminated | 64 |
| Withdrawn | 26 |
| Recruiting | 13 |
| Unknown status | 11 |
| Not yet recruiting | 5 |
| Suspended | 2 |
| Active, not recruiting | 1 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Antonios Likourezos | 14 |
| Duke University | 12 |
| University of California, San Diego | 12 |
| Northwestern University | 11 |
| Oregon Health and Science University | 10 |
| Montefiore Medical Center | 8 |
| Hospital for Special Surgery, New York | 6 |
| Pacira Pharmaceuticals, Inc | 6 |
| Wake Forest University Health Sciences | 6 |
| Columbia University | 5 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Pain | 341 |
| Agnosia | 49 |
| Postoperative Pain | 33 |
| Acute Pain | 14 |
| Back Pain | 9 |
| Chronic Pain | 9 |
| Emergencies | 8 |
| Opioid-Related Disorders | 8 |
| Anxiety Disorders | 7 |
| Osteoarthritis | 7 |
Trials
Showing 1 to 25 of 341. Each trial links to its page on Pharma Observatory.
241 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
No changes to these trials in the last 7 days.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.