Clinical trials
Observational alpha 1-Antitrypsin Deficiency trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
25 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 1 |
| 2001 | 1 |
| 2002 | 1 |
| 2007 | 3 |
| 2008 | 1 |
| 2013 | 4 |
| 2015 | 2 |
| 2016 | 2 |
| 2018 | 2 |
| 2019 | 1 |
| 2022 | 1 |
| 2024 | 1 |
| 2025 | 1 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 13 |
| Recruiting | 6 |
| Active, not recruiting | 2 |
| Terminated | 2 |
| Enrolling by invitation | 1 |
| Suspended | 1 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| University of Florida | 4 |
| Columbia University | 3 |
| Medical University of South Carolina | 3 |
| National Heart, Lung, and Blood Institute (NHLBI) | 3 |
| Alpha-1 Foundation | 2 |
| Arbor Research Collaborative for Health | 2 |
| Adverum Biotechnologies, Inc. | 1 |
| Biocerna LLC | 1 |
| Coram Clinical Trials | 1 |
| National Center for Research Resources (NCRR) | 1 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| alpha 1-Antitrypsin Deficiency | 25 |
| Pulmonary Disease, Chronic Obstructive | 6 |
| Genetic Diseases, Inborn | 5 |
| Emphysema | 4 |
| Alagille Syndrome | 2 |
| Cholestasis | 2 |
| Cystic Fibrosis | 2 |
| Fibrosis | 2 |
| Liver Cirrhosis | 2 |
| Lung Diseases | 2 |
Trials
Showing 1 to 25 of 25. Each trial links to its page on Pharma Observatory.
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
No changes to these trials in the last 7 days.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.