Clinical trials
Completed alpha 1-Antitrypsin Deficiency trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
45 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 1 |
| 2001 | 1 |
| 2003 | 1 |
| 2004 | 2 |
| 2006 | 4 |
| 2007 | 2 |
| 2008 | 1 |
| 2010 | 3 |
| 2012 | 3 |
| 2013 | 4 |
| 2014 | 2 |
| 2015 | 2 |
| 2016 | 3 |
| 2017 | 4 |
| 2018 | 2 |
| 2019 | 3 |
| 2020 | 1 |
| 2021 | 1 |
| 2022 | 1 |
| 2023 | 2 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 45 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Grifols Therapeutics LLC | 6 |
| Baxalta now part of Shire | 4 |
| Medical University of South Carolina | 4 |
| Vertex Pharmaceuticals Incorporated | 3 |
| Adverum Biotechnologies, Inc. | 2 |
| Kamada, Ltd. | 2 |
| National Heart, Lung, and Blood Institute (NHLBI) | 2 |
| University of Florida | 2 |
| University of Massachusetts, Worcester | 2 |
| Alpha-1 Foundation | 1 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| alpha 1-Antitrypsin Deficiency | 45 |
| Emphysema | 13 |
| Pulmonary Disease, Chronic Obstructive | 10 |
| Lung Diseases | 5 |
| Pulmonary Emphysema | 5 |
| Genetic Diseases, Inborn | 3 |
| Cystic Fibrosis | 2 |
| Liver Cirrhosis | 2 |
| Liver Diseases | 2 |
| Lung Diseases, Obstructive | 2 |
Trials
Showing 1 to 25 of 45. Each trial links to its page on Pharma Observatory.
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
No changes to these trials in the last 7 days.
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