Active, not recruiting trials in Italy: Trial Insights

Filters: Status: Active, not recruiting Country / region: Italy Clear all

1,956 trials match Source: ClinicalTrials.gov registrations

Trials started per year
Category	Trials
2005	2
2007	1
2008	2
2009	2
2010	6
2011	3
2012	8
2013	17
2014	22
2015	28
2016	29
2017	59
2018	82
2019	145
2020	159
2021	251
2022	261
2023	292
2024	328
2025	209
2026	48

Trials by status
Category	Trials
Active, not recruiting	1,956

Top lead sponsors
Category	Trials
AstraZeneca	96
Novartis Pharmaceuticals	82
Hoffmann-La Roche	74
Fondazione Policlinico Universitario Agostino Gemelli IRCCS	65
Merck Sharp & Dohme LLC	50
Janssen Research & Development, LLC	48
AbbVie	47
Eli Lilly and Company	34
Bristol-Myers Squibb	33
IRCCS Azienda Ospedaliero-Universitaria di Bologna	32

Top conditions
Category	Trials
Carcinoma, Non-Small-Cell Lung	118
Breast Neoplasms	96
Neoplasms	68
Neoplasm Metastasis	40
Multiple Myeloma	38
Prostatic Neoplasms	36
Colorectal Neoplasms	35
Ovarian Neoplasms	33
Melanoma	32
Recurrence	32

Trials

Showing 1 to 25 of 1,956. Each trial links to its page on Pharma Observatory.

Real-World Effectiveness of Conservative Treatment in Idiopathic Scoliosis NCT07873554ObservationalActive, not recruitingIstituto Scientifico Italiano Colonna VertebraleStarted 2026
Evaluation of the Rapid Diagnostic Test SsRT+ for Strongyloides Stercoralis NCT07876622Not applicableActive, not recruitingIRCCS Sacro Cuore Don Calabria di NegrarStarted 2026
Optimizing Risk Assessment Through cfDNA in Pancreatic Neuroendocrine Tumors for Clinical Evaluation NCT07817225ObservationalActive, not recruitingMassimo FalconiStarted 2026
Randomized Prospective Trial on the Cost-Effectiveness of Photon-Counting CT Versus Energy-Integrating Detector CT in Suspected Chronic Coronary Syndrome NCT07831304Not applicableActive, not recruitingIRCCS San RaffaeleStarted 2026
Early Rehabilitation in Patients Following Major Cardiac Surgery: Changes in Functional Capacity and Energy Efficiency in Walking and ADLs. NCT07843316Not applicableActive, not recruitingIstituti Clinici Scientifici Maugeri SpAStarted 2026
EXIT-CVD Project: Evidence Based Exit Strategies for the Cardiovascular Disease Continuum Trough Early Detection, Treatment and Evaluation NCT07857031Not applicableActive, not recruitingCentro Cardiologico MonzinoStarted 2026
Role of NAC in cT0 Muscle-invasive Bladder Cancer After Maximal TURBt NCT05776758Phase 3Active, not recruitingRegina Elena Cancer InstituteStarted 2026
Norovirus Prevalence and Fecal Microbiome Characterization Through Metagenomic and Metatranscriptomic Analyses NCT07866469Not applicableActive, not recruitingIRCCS Sacro Cuore Don Calabria di NegrarStarted 2026
Advancing Risk Stratification in Endometrial Cancer NCT07746024ObservationalActive, not recruitingFondazione Policlinico Universitario Agostino Gemelli IRCCSStarted 2026
Ten Years Follow-up After the Arthroscopic Repair of Osteochondral Lesions of the Talus Via Autologous Matrix-induced Chondrogenesis (AMIC) NCT07725770ObservationalActive, not recruitingI.R.C.C.S Ospedale Galeazzi-Sant'AmbrogioStarted 2026
The Aim of the Study is to Characterize Patients Exhibiting Muscular Atrophy and Weakness Who Require a Muscle Biopsy for Diagnosis (IBM vs Atypical MND), Through an Innovative Technique Which Enables the Evaluation of the Neuromuscular Junction Involvement in Each Condition NCT07796776ObservationalActive, not recruitingIRCCS San RaffaeleStarted 2026
Survival, Clinical and Radiological Outcomes of Total Ankle Arthroplasty With Lateral Transfibular Approach With a Minimum 10 Years Follow up NCT07732153ObservationalActive, not recruitingI.R.C.C.S Ospedale Galeazzi-Sant'AmbrogioStarted 2026
The Use of Artificial Intelligence for Ultrasound Screening of Ovarian Cancer in Postmenopausal Women NCT07660718ObservationalActive, not recruitingIRCCS Azienda Ospedaliero-Universitaria di BolognaStarted 2026
A Study to Evaluate the Efficacy and Safety of Concomitant Use of Eplontersen and ALXN2220 Compared With Eplontersen and Placebo for Adults Participants With ATTR-CM NCT07608354Phase 2Active, not recruitingAstraZenecaStarted 2026
Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments NCT07468071Phase 1/2Active, not recruitingNovartis PharmaceuticalsStarted 2026
Open-Label Extension Study of BBP-418 (Ribitol) for LGMD2I/R9 NCT07678775Phase 3Active, not recruitingML Bio Solutions, Inc.Started 2026
Sleep Medicine Education in Dental Schools and Residency Programs in Italian Universities NCT07624110ObservationalActive, not recruitingFondazione Policlinico Universitario Agostino Gemelli IRCCSStarted 2026
Radiomics Analysis of CMR Imaging for Arrhythmic Risk Prediction in Hypertrophic Cardiomyopathy, With Longitudinal Risk Reassessment After Mavacamten Therapy in Obstructive Patients NCT07695272ObservationalActive, not recruitingCentro Cardiologico MonzinoStarted 2026
Long Term Management and Outcomes of Surgical and Non Surgical Infective Endocarditis NCT07825272ObservationalActive, not recruitingCentro Cardiologico MonzinoStarted 2026
Monitoring of the Sympathetic/Vagal Balance Through Multiparametric Analysis of Heart Rate Variability (HRV) NCT07471802ObservationalActive, not recruitingFondazione Policlinico Universitario Agostino Gemelli IRCCSStarted 2026
Burnout and Well-Being in Healthcare Workers Participating in Workplace Yoga NCT07786584ObservationalActive, not recruitingIRCCS Centro Neurolesi Bonino PulejoStarted 2026
A Study to Investigate the Long-term Safety, Tolerability and Efficacy of Balinatunfib in Participants With Crohn's Disease or Ulcerative Colitis (SPECIFI-IBD-LTS) NCT07222189Phase 2Active, not recruitingSanofiStarted 2026
Patients With Primary Biliary Cholangitis(PBC) NCT07629128ObservationalActive, not recruitingFondazione Policlinico Universitario Agostino Gemelli IRCCSStarted 2026
Effects of Lokomat Training on Dynamic Postural Stability in Incomplete Spinal Cord Injury NCT07621900Not applicableActive, not recruitingI.R.C.C.S. Fondazione Santa LuciaStarted 2026
Evaluation of Safety of Complex Pedicle Screw Trajectories Using Patient-Specific Guides (MySpine, Medacta) NCT07790068ObservationalActive, not recruitingI.R.C.C.S Ospedale Galeazzi-Sant'AmbrogioStarted 2026

1,856 more trials match. See them on Pharma Observatory

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease NCT06332534Completion date change2034-12-31 to 2031-01-31October 18, 2026
A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab NCT06389136Completion date change2027-03-31 to 2027-05-31October 18, 2026
A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis NCT06461897Completion date change2030-07-31 to 2029-11-30October 18, 2026
An Extension Study Evaluating 6-week Treatment Cycles of Rozanolixizumab in Pediatric Study Participants With Generalized Myasthenia Gravis NCT06540144Completion date change2027-08-17 to 2027-10-05October 18, 2026
A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis NCT06655155Completion date change2027-09-30 to 2027-10-31October 18, 2026
Cardiac Resynchronization Therapy in Previously Untreatable and High Risk Upgrade Patients NCT02922036Completion date change2026-06-30 to 2027-11-30October 18, 2026
A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib NCT03673501Completion date change2026-12-31 to 2027-12-31October 18, 2026
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease NCT05271409Enrollment change132 to 139October 18, 2026
A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis NCT06329401Enrollment change375 to 398October 18, 2026
Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease NCT06332534Enrollment change110 to 111October 18, 2026

Go deeper on Pharma Observatory

Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.

Visit Pharma Observatory