Clinical trials
Phase 1 trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
27,413 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 199 |
| 2001 | 219 |
| 2002 | 281 |
| 2003 | 361 |
| 2004 | 511 |
| 2005 | 614 |
| 2006 | 755 |
| 2007 | 898 |
| 2008 | 1,008 |
| 2009 | 1,085 |
| 2010 | 1,105 |
| 2011 | 1,130 |
| 2012 | 1,051 |
| 2013 | 1,131 |
| 2014 | 1,253 |
| 2015 | 1,130 |
| 2016 | 1,167 |
| 2017 | 1,223 |
| 2018 | 1,286 |
| 2019 | 1,314 |
| 2020 | 1,258 |
| 2021 | 1,354 |
| 2022 | 1,279 |
| 2023 | 1,224 |
| 2024 | 1,237 |
| 2025 | 1,180 |
| 2026 | 1,103 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 18,325 |
| Terminated | 3,155 |
| Recruiting | 2,533 |
| Active, not recruiting | 1,335 |
| Withdrawn | 779 |
| Unknown status | 736 |
| Not yet recruiting | 344 |
| Suspended | 132 |
| Enrolling by invitation | 74 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| National Cancer Institute (NCI) | 932 |
| National Institute of Allergy and Infectious Diseases (NIAID) | 767 |
| Pfizer | 656 |
| M.D. Anderson Cancer Center | 514 |
| Eli Lilly and Company | 500 |
| GlaxoSmithKline | 413 |
| AstraZeneca | 404 |
| Bristol-Myers Squibb | 364 |
| Mayo Clinic | 361 |
| Memorial Sloan Kettering Cancer Center | 360 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Neoplasms | 1,388 |
| Breast Neoplasms | 963 |
| Carcinoma, Non-Small-Cell Lung | 895 |
| Leukemia, Myeloid, Acute | 767 |
| Neoplasm Metastasis | 698 |
| HIV Infections | 668 |
| Melanoma | 632 |
| Lymphoma | 581 |
| Prostatic Neoplasms | 568 |
| Multiple Myeloma | 552 |
Trials
Showing 1 to 25 of 27,413. Each trial links to its page on Pharma Observatory.
27,313 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.