Clinical trials
Completed Phase 1 trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
18,325 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 168 |
| 2001 | 181 |
| 2002 | 248 |
| 2003 | 317 |
| 2004 | 438 |
| 2005 | 520 |
| 2006 | 628 |
| 2007 | 730 |
| 2008 | 815 |
| 2009 | 893 |
| 2010 | 917 |
| 2011 | 923 |
| 2012 | 868 |
| 2013 | 928 |
| 2014 | 989 |
| 2015 | 864 |
| 2016 | 859 |
| 2017 | 876 |
| 2018 | 896 |
| 2019 | 845 |
| 2020 | 763 |
| 2021 | 737 |
| 2022 | 673 |
| 2023 | 544 |
| 2024 | 440 |
| 2025 | 300 |
| 2026 | 83 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 18,325 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| National Institute of Allergy and Infectious Diseases (NIAID) | 661 |
| National Cancer Institute (NCI) | 604 |
| Pfizer | 527 |
| Eli Lilly and Company | 408 |
| GlaxoSmithKline | 360 |
| AstraZeneca | 326 |
| Bristol-Myers Squibb | 309 |
| Mayo Clinic | 256 |
| M.D. Anderson Cancer Center | 255 |
| Memorial Sloan Kettering Cancer Center | 240 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Neoplasms | 903 |
| HIV Infections | 598 |
| Breast Neoplasms | 570 |
| Carcinoma, Non-Small-Cell Lung | 420 |
| Leukemia, Myeloid, Acute | 382 |
| Lymphoma | 374 |
| Neoplasm Metastasis | 354 |
| Melanoma | 350 |
| Prostatic Neoplasms | 319 |
| Diabetes Mellitus, Type 2 | 312 |
Trials
Showing 1 to 25 of 18,325. Each trial links to its page on Pharma Observatory.
18,225 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.