Clinical trials
Terminated Phase 1 trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
3,155 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 15 |
| 2001 | 17 |
| 2002 | 18 |
| 2003 | 36 |
| 2004 | 49 |
| 2005 | 71 |
| 2006 | 90 |
| 2007 | 124 |
| 2008 | 134 |
| 2009 | 133 |
| 2010 | 130 |
| 2011 | 137 |
| 2012 | 130 |
| 2013 | 122 |
| 2014 | 160 |
| 2015 | 163 |
| 2016 | 176 |
| 2017 | 180 |
| 2018 | 185 |
| 2019 | 216 |
| 2020 | 188 |
| 2021 | 201 |
| 2022 | 164 |
| 2023 | 132 |
| 2024 | 103 |
| 2025 | 37 |
| 2026 | 2 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Terminated | 3,155 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| National Cancer Institute (NCI) | 141 |
| Pfizer | 97 |
| M.D. Anderson Cancer Center | 82 |
| Washington University School of Medicine | 57 |
| Novartis Pharmaceuticals | 56 |
| Amgen | 39 |
| AbbVie | 37 |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 37 |
| National Institute of Allergy and Infectious Diseases (NIAID) | 36 |
| AstraZeneca | 35 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Neoplasms | 247 |
| Carcinoma, Non-Small-Cell Lung | 232 |
| Leukemia, Myeloid, Acute | 169 |
| Breast Neoplasms | 149 |
| Melanoma | 147 |
| Neoplasm Metastasis | 133 |
| Multiple Myeloma | 119 |
| Colorectal Neoplasms | 111 |
| Lymphoma | 111 |
| Recurrence | 104 |
Trials
Showing 1 to 25 of 3,155. Each trial links to its page on Pharma Observatory.
3,055 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.