Clinical trials
Phase 4 trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
10,669 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 53 |
| 2001 | 84 |
| 2002 | 156 |
| 2003 | 260 |
| 2004 | 329 |
| 2005 | 372 |
| 2006 | 456 |
| 2007 | 438 |
| 2008 | 500 |
| 2009 | 494 |
| 2010 | 455 |
| 2011 | 421 |
| 2012 | 417 |
| 2013 | 440 |
| 2014 | 428 |
| 2015 | 413 |
| 2016 | 462 |
| 2017 | 508 |
| 2018 | 493 |
| 2019 | 507 |
| 2020 | 440 |
| 2021 | 458 |
| 2022 | 396 |
| 2023 | 364 |
| 2024 | 357 |
| 2025 | 343 |
| 2026 | 405 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 6,661 |
| Terminated | 1,402 |
| Recruiting | 879 |
| Withdrawn | 588 |
| Unknown status | 555 |
| Active, not recruiting | 267 |
| Not yet recruiting | 195 |
| Enrolling by invitation | 93 |
| Suspended | 29 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Massachusetts General Hospital | 209 |
| Mayo Clinic | 188 |
| University of California, San Francisco | 165 |
| Emory University | 143 |
| Duke University | 142 |
| GlaxoSmithKline | 112 |
| NYU Langone Health | 108 |
| University of Texas Southwestern Medical Center | 105 |
| The University of Texas Health Science Center, Houston | 99 |
| Stanford University | 97 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Postoperative Pain | 345 |
| Pain | 341 |
| Diabetes Mellitus, Type 2 | 294 |
| Diabetes Mellitus | 215 |
| Obesity | 198 |
| Schizophrenia | 192 |
| Major Depressive Disorder | 185 |
| Hypertension | 179 |
| HIV Infections | 156 |
| Bipolar Disorder | 155 |
Trials
Showing 1 to 25 of 10,669. Each trial links to its page on Pharma Observatory.
10,569 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.