Clinical trials
Terminated Phase 4 trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
1,402 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 2 |
| 2001 | 4 |
| 2002 | 9 |
| 2003 | 21 |
| 2004 | 35 |
| 2005 | 47 |
| 2006 | 69 |
| 2007 | 66 |
| 2008 | 73 |
| 2009 | 68 |
| 2010 | 64 |
| 2011 | 58 |
| 2012 | 77 |
| 2013 | 75 |
| 2014 | 72 |
| 2015 | 53 |
| 2016 | 85 |
| 2017 | 95 |
| 2018 | 92 |
| 2019 | 79 |
| 2020 | 66 |
| 2021 | 68 |
| 2022 | 59 |
| 2023 | 37 |
| 2024 | 12 |
| 2025 | 9 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Terminated | 1,402 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Massachusetts General Hospital | 33 |
| Duke University | 29 |
| University of California, San Francisco | 22 |
| Emory University | 21 |
| Columbia University | 20 |
| Mayo Clinic | 20 |
| Weill Medical College of Cornell University | 20 |
| Northwestern University | 18 |
| Pfizer | 17 |
| University of Chicago | 17 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Pain | 64 |
| Diabetes Mellitus, Type 2 | 41 |
| Postoperative Pain | 38 |
| Diabetes Mellitus | 28 |
| Agnosia | 26 |
| Obesity | 22 |
| Asthma | 21 |
| Heart Failure | 21 |
| Major Depressive Disorder | 21 |
| Hypertension | 19 |
Trials
Showing 1 to 25 of 1,402. Each trial links to its page on Pharma Observatory.
1,302 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
No changes to these trials in the last 7 days.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.