Recruiting trials in the United States: Trial Insights

Filters: Status: Recruiting Country / region: United States Clear all

22,207 trials match Source: ClinicalTrials.gov registrations

Trials started per year
Category	Trials
2000	21
2001	27
2002	26
2003	28
2004	31
2005	35
2006	32
2007	48
2008	35
2009	48
2010	67
2011	68
2012	70
2013	105
2014	133
2015	165
2016	199
2017	263
2018	358
2019	501
2020	619
2021	1,020
2022	1,520
2023	2,500
2024	3,742
2025	5,432
2026	4,992

Trials by status
Category	Trials
Recruiting	22,207

Top lead sponsors
Category	Trials
M.D. Anderson Cancer Center	508
Mayo Clinic	502
Memorial Sloan Kettering Cancer Center	309
Massachusetts General Hospital	308
National Cancer Institute (NCI)	298
VA Office of Research and Development	275
University of California, San Francisco	243
Stanford University	237
Johns Hopkins University	229
University of Colorado, Denver	222

Top conditions
Category	Trials
Breast Neoplasms	669
Neoplasms	626
Prostatic Neoplasms	485
Obesity	481
Carcinoma, Non-Small-Cell Lung	440
Lung Neoplasms	351
Colorectal Neoplasms	340
Neoplasm Metastasis	290
Stroke	284
Leukemia, Myeloid, Acute	277

Trials

Showing 1 to 25 of 22,207. Each trial links to its page on Pharma Observatory.

Imaging Oxidative Metabolism and Neurotransmitter Synthesis in the Human Brain NCT03849963ObservationalRecruitingUniversity of Texas Southwestern Medical CenterStarted 2030
Regulating Together for Intellectual Disability and Autism: A Group Behavioral Therapy for for Emotion Dysregulation NCT07624448Not applicableRecruitingChildren's Mercy Hospital Kansas CityStarted 2027
Unconscious Mind Training NCT07597603Not applicableRecruitingDream Video LLCStarted 2027
Monitoring Breast Cancer Immunotherapy Treatment With Advanced Positron Emission Tomography Magnetic Resonance Imaging (PET/MRI) NCT04861077Phase 1RecruitingUniversity of Alabama at BirminghamStarted 2027
Testing the Addition of Iberdomide to Therapy in People With Neuroblastoma That Has Come Back, Not Responded to Treatment, or Gotten Worse NCT07437963Phase 1/2RecruitingNational Cancer Institute (NCI)Started 2027
TMS to Improve Recovery Outcomes Among Patients With Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD) NCT07171359Not applicableRecruitingWashington State UniversityStarted 2027
Testing the Combination of Anti-Cancer Drugs, Selumetinib and DS-8201a (Trastuzumab Deruxtecan), for Advanced Pancreatic Ductal Adenocarcinoma NCT07619521Phase 1/2RecruitingNational Cancer Institute (NCI)Started 2027
Testing the Combination of Anti-Cancer Drugs, Botensilimab (AGEN1181) and Balstilimab (AGEN2034), After Standard Treatment for Colorectal Cancer, Combat Trial NCT07551596Phase 2RecruitingNational Cancer Institute (NCI)Started 2027
Testing the Investigational Medication Combination of Daratumumab and Teclistamab Compared to the Usual Treatment (Daratumumab, Pomalidomide, Dexamethasone or Daratumumab, Carfilzomib, Dexamethasone) for Patients With High-risk Multiple Myeloma Refractory or in First Relapse NCT06948084Phase 2RecruitingNational Cancer Institute (NCI)Started 2027
Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell Renal Cell Carcinoma, NEO RoBOT Trial NCT07516366Phase 2RecruitingNational Cancer Institute (NCI)Started 2027
A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information NCT07621614Phase 2RecruitingChildren's Oncology GroupStarted 2027
Breakthrough - T1DM and Chronic Kidney Disease NCT07592000Phase 1/2RecruitingUniversity of ChicagoStarted 2027
Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM Trial NCT07605416Phase 2RecruitingNational Cancer Institute (NCI)Started 2027
Testing the Investigational Medication Combination of Teclistamab and Pomalidomide Compared to the Usual Treatment (Carfilzomib, Pomalidomide, and Dexamethasone) for Patients With Multiple Myeloma Who Have Relapsed Shortly After Treatment NCT07463807Phase 1/2RecruitingNational Cancer Institute (NCI)Started 2027
Testing the Effect of Teclistamab on Recurrent Plasmablastic Lymphoma NCT07332507Phase 1RecruitingNational Cancer Institute (NCI)Started 2027
Adding Surgery and Radiation to the Usual Treatment for HER2-Positive Breast Cancer That Had Already Spread at Diagnosis NCT07578116Phase 3RecruitingSWOG Cancer Research NetworkStarted 2027
Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial NCT07388524Phase 3RecruitingNational Cancer Institute (NCI)Started 2027
Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea. NCT06587256Phase 2RecruitingJohns Hopkins UniversityStarted 2027
Mindfulness Intervention to Reduce Patient Reported Symptoms in Patients With Chronic Graft-Versus-Host Disease NCT07733141Not applicableRecruitingCity of Hope Medical CenterStarted 2027
A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients NCT06424522Not applicableRecruitingOhio State University Comprehensive Cancer CenterStarted 2027
Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma NCT07156227Phase 1RecruitingNational Cancer Institute (NCI)Started 2027
Adapting Youth Nominated Support Team (YST) to Prevent Suicide NCT07559955Not applicableRecruitingColumbia UniversityStarted 2027
Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures NCT03258658Phase 1RecruitingWake Forest University Health SciencesStarted 2027
Music Interventions During Wide-Awake Hand Surgery NCT05472909Not applicableRecruitingUniversity of Wisconsin, MadisonStarted 2027
DK222 Study at Hopkins NCT07140315Phase 1RecruitingSidney Kimmel Comprehensive Cancer Center at Johns HopkinsStarted 2027

22,107 more trials match. See them on Pharma Observatory

Tasting Plant Forward Meals NCT07202988Completion date change2026-12-31 to 2027-04-30October 18, 2026
Virtual Reality Viewing of Unaltered Streetscape Versus Digitally Manipulated Opposite Streetscape to Assess Psychosocial Response in Participants NCT07216534Completion date change2026-12-31 to 2028-01-31October 18, 2026
A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients (MOTION-P) NCT07219771Completion date change2027-10-31 to 2027-12-30October 18, 2026
Treatment of Atopic Dermatitis and Alopecia Areata With Abrocitinib in Individuals With Down Syndrome NCT07242638Completion date change2028-03-03 to 2029-02-23October 18, 2026
Elite AF IDE Trial (Elite AF) NCT07287436Completion date changenot stated to 2032-11-30October 18, 2026
Cefotetan Therapy for Escherichia Coli Infections NCT07318584Completion date change2028-08-31 to 2029-04-30October 18, 2026
Feasibility Study of the Flash-Sole: A Wearable Midsole With Soft Actuators for Walking Assistance NCT07507006Completion date change2026-09-30 to 2028-06-01October 18, 2026
Fluorescence-Guided Surgical Resection for Reducing Unexpected Positive Margins in Patients With Sarcoma, SarcoSIGHT Trial NCT07650656Completion date change2028-05-11 to 2029-12-17October 18, 2026
Virtual Reality for SCD VOC NCT07674277Completion date change2027-12-31 to 2028-03-31October 18, 2026
Comparing Two Weight Loss Programs for the Prevention of Kidney Cancer Progression Among Patients With Small Renal Masses on Active Surveillance NCT07714018Completion date change2028-09-01 to 2028-11-01October 18, 2026

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