Clinical trials
Major Depressive Disorder trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
1,471 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 5 |
| 2001 | 14 |
| 2002 | 25 |
| 2003 | 30 |
| 2004 | 38 |
| 2005 | 40 |
| 2006 | 65 |
| 2007 | 50 |
| 2008 | 61 |
| 2009 | 49 |
| 2010 | 69 |
| 2011 | 84 |
| 2012 | 64 |
| 2013 | 55 |
| 2014 | 59 |
| 2015 | 54 |
| 2016 | 58 |
| 2017 | 64 |
| 2018 | 50 |
| 2019 | 50 |
| 2020 | 53 |
| 2021 | 72 |
| 2022 | 52 |
| 2023 | 73 |
| 2024 | 68 |
| 2025 | 71 |
| 2026 | 66 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 1,007 |
| Recruiting | 158 |
| Terminated | 133 |
| Withdrawn | 45 |
| Unknown status | 42 |
| Active, not recruiting | 38 |
| Not yet recruiting | 25 |
| Enrolling by invitation | 16 |
| Suspended | 7 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Massachusetts General Hospital | 81 |
| National Institute of Mental Health (NIMH) | 63 |
| New York State Psychiatric Institute | 48 |
| Eli Lilly and Company | 39 |
| University of California, Los Angeles | 35 |
| Stanford University | 34 |
| Mclean Hospital | 32 |
| Janssen Research & Development, LLC | 31 |
| Otsuka Pharmaceutical Development & Commercialization, Inc. | 29 |
| Forest Laboratories | 27 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Major Depressive Disorder | 1,471 |
| Bipolar Disorder | 129 |
| Depressive Disorder | 115 |
| Mood Disorders | 81 |
| Depressive Disorder, Treatment-Resistant | 77 |
| Anxiety Disorders | 71 |
| Schizophrenia | 64 |
| Stress Disorders, Post-Traumatic | 60 |
| Psychotic Disorders | 53 |
| Mental Disorders | 45 |
Trials
Showing 1 to 25 of 1,471. Each trial links to its page on Pharma Observatory.
1,371 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
Go deeper on Pharma Observatory
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