Clinical trials
Phase 3 Major Depressive Disorder trials
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
388 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2001 | 6 |
| 2002 | 16 |
| 2003 | 9 |
| 2004 | 16 |
| 2005 | 21 |
| 2006 | 27 |
| 2007 | 13 |
| 2008 | 15 |
| 2009 | 18 |
| 2010 | 24 |
| 2011 | 29 |
| 2012 | 18 |
| 2013 | 13 |
| 2014 | 14 |
| 2015 | 12 |
| 2016 | 10 |
| 2017 | 6 |
| 2018 | 16 |
| 2019 | 10 |
| 2020 | 12 |
| 2021 | 10 |
| 2022 | 9 |
| 2023 | 8 |
| 2024 | 12 |
| 2025 | 19 |
| 2026 | 16 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 289 |
| Recruiting | 31 |
| Terminated | 30 |
| Withdrawn | 13 |
| Not yet recruiting | 8 |
| Unknown status | 7 |
| Active, not recruiting | 7 |
| Suspended | 2 |
| Enrolling by invitation | 1 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Eli Lilly and Company | 21 |
| H. Lundbeck A/S | 21 |
| Forest Laboratories | 18 |
| Otsuka Pharmaceutical Development & Commercialization, Inc. | 18 |
| Wyeth is now a wholly owned subsidiary of Pfizer | 18 |
| AstraZeneca | 14 |
| Janssen Research & Development, LLC | 13 |
| Takeda | 13 |
| Sanofi | 11 |
| Naurex, Inc, an affiliate of Allergan plc | 10 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Major Depressive Disorder | 388 |
| Depressive Disorder | 35 |
| Mood Disorders | 13 |
| Depressive Disorder, Treatment-Resistant | 12 |
| Mental Disorders | 12 |
| Bipolar Disorder | 11 |
| Psychotic Disorders | 11 |
| Sleep Initiation and Maintenance Disorders | 8 |
| Anxiety Disorders | 6 |
| Schizophrenia | 5 |
Trials
Showing 1 to 25 of 388. Each trial links to its page on Pharma Observatory.
288 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
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