Clinical trials
Completed Major Depressive Disorder trials
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
1,789 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2000 | 7 |
| 2001 | 19 |
| 2002 | 37 |
| 2003 | 33 |
| 2004 | 53 |
| 2005 | 64 |
| 2006 | 81 |
| 2007 | 81 |
| 2008 | 86 |
| 2009 | 84 |
| 2010 | 91 |
| 2011 | 117 |
| 2012 | 93 |
| 2013 | 71 |
| 2014 | 81 |
| 2015 | 86 |
| 2016 | 89 |
| 2017 | 75 |
| 2018 | 67 |
| 2019 | 72 |
| 2020 | 67 |
| 2021 | 94 |
| 2022 | 80 |
| 2023 | 55 |
| 2024 | 47 |
| 2025 | 19 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 1,789 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Massachusetts General Hospital | 58 |
| Eli Lilly and Company | 54 |
| National Institute of Mental Health (NIMH) | 47 |
| New York State Psychiatric Institute | 39 |
| Centre for Addiction and Mental Health | 32 |
| H. Lundbeck A/S | 31 |
| AstraZeneca | 30 |
| Otsuka Pharmaceutical Development & Commercialization, Inc. | 28 |
| University of California, Los Angeles | 28 |
| Forest Laboratories | 27 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Major Depressive Disorder | 1,789 |
| Bipolar Disorder | 145 |
| Depressive Disorder | 141 |
| Anxiety Disorders | 86 |
| Mood Disorders | 81 |
| Schizophrenia | 72 |
| Depressive Disorder, Treatment-Resistant | 68 |
| Psychotic Disorders | 54 |
| Mental Disorders | 47 |
| Stress Disorders, Post-Traumatic | 46 |
Trials
Showing 1 to 25 of 1,789. Each trial links to its page on Pharma Observatory.
1,689 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
No changes to these trials in the last 7 days.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.