Clinical trials
Down Syndrome trials in the United States
Search ClinicalTrials.gov registrations by keyword, then narrow by condition, phase, status, country and start year.
200 trials match Source: ClinicalTrials.gov registrations
Trials started per year
By phase, 2000 to 2026.
| Category | Trials |
|---|---|
| 2001 | 2 |
| 2002 | 1 |
| 2004 | 1 |
| 2005 | 2 |
| 2006 | 3 |
| 2007 | 2 |
| 2008 | 7 |
| 2009 | 10 |
| 2010 | 8 |
| 2011 | 5 |
| 2012 | 8 |
| 2013 | 10 |
| 2014 | 10 |
| 2015 | 13 |
| 2016 | 6 |
| 2017 | 5 |
| 2018 | 13 |
| 2019 | 8 |
| 2020 | 11 |
| 2021 | 16 |
| 2022 | 9 |
| 2023 | 13 |
| 2024 | 7 |
| 2025 | 10 |
| 2026 | 18 |
Status
Trials by registry status. Select a bar to filter.
| Category | Trials |
|---|---|
| Completed | 114 |
| Recruiting | 39 |
| Terminated | 21 |
| Unknown status | 10 |
| Active, not recruiting | 7 |
| Not yet recruiting | 4 |
| Enrolling by invitation | 3 |
| Withdrawn | 2 |
Top lead sponsors
A sponsor with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| University of Colorado, Denver | 12 |
| Natera, Inc. | 8 |
| Sequenom, Inc. | 8 |
| University of Kansas Medical Center | 8 |
| Children's Hospital Medical Center, Cincinnati | 7 |
| Hoffmann-La Roche | 6 |
| Oregon Health and Science University | 5 |
| University of Michigan | 5 |
| Children's Hospital of Philadelphia | 4 |
| Duke University | 4 |
Top conditions
MeSH conditions the trials were registered with, not their broader categories. A condition with a page on Pharma Observatory links to it.
| Category | Trials |
|---|---|
| Down Syndrome | 200 |
| Alzheimer Disease | 21 |
| Trisomy 18 Syndrome | 21 |
| Trisomy 13 Syndrome | 19 |
| Sleep Apnea, Obstructive | 16 |
| Turner Syndrome | 13 |
| Aneuploidy | 12 |
| Intellectual Disability | 11 |
| Cerebral Palsy | 8 |
| Sex Chromosome Aberrations | 7 |
Trials
Showing 1 to 25 of 200. Each trial links to its page on Pharma Observatory.
100 more trials match. See them on Pharma Observatory
Recently changed trials
Changes observed in the last 7 days, newest first, site-count changes left out. Source: ClinicalTrials.gov.
Go deeper on Pharma Observatory
Pharma Observatory connects clinical trials, sponsors, sites and investigators in one searchable platform.